Live cell imaging of single genomic loci with quantum dot-labeled TALEs

Visualizing single genomic loci in living cells remains technically challenging. Here the authors adopt a strategy of labelling a pair of transcription activator-like effectors (TALEs) with differently coloured quantum dots and use them to identify integrated HIV-1 proviral DNA sequences in living c...

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Autores principales:	Yingxin Ma, Mingxiu Wang, Wei Li, Zhiping Zhang, Xiaowei Zhang, Tianwei Tan, Xian-En Zhang, Zongqiang Cui
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d299f1264a2a475692ab68c7f85c2847
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spelling	oai:doaj.org-article:d299f1264a2a475692ab68c7f85c28472021-12-02T17:06:19ZLive cell imaging of single genomic loci with quantum dot-labeled TALEs10.1038/ncomms153182041-1723https://doaj.org/article/d299f1264a2a475692ab68c7f85c28472017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15318https://doaj.org/toc/2041-1723Visualizing single genomic loci in living cells remains technically challenging. Here the authors adopt a strategy of labelling a pair of transcription activator-like effectors (TALEs) with differently coloured quantum dots and use them to identify integrated HIV-1 proviral DNA sequences in living cells.Yingxin MaMingxiu WangWei LiZhiping ZhangXiaowei ZhangTianwei TanXian-En ZhangZongqiang CuiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yingxin Ma Mingxiu Wang Wei Li Zhiping Zhang Xiaowei Zhang Tianwei Tan Xian-En Zhang Zongqiang Cui Live cell imaging of single genomic loci with quantum dot-labeled TALEs
description	Visualizing single genomic loci in living cells remains technically challenging. Here the authors adopt a strategy of labelling a pair of transcription activator-like effectors (TALEs) with differently coloured quantum dots and use them to identify integrated HIV-1 proviral DNA sequences in living cells.
format	article
author	Yingxin Ma Mingxiu Wang Wei Li Zhiping Zhang Xiaowei Zhang Tianwei Tan Xian-En Zhang Zongqiang Cui
author_facet	Yingxin Ma Mingxiu Wang Wei Li Zhiping Zhang Xiaowei Zhang Tianwei Tan Xian-En Zhang Zongqiang Cui
author_sort	Yingxin Ma
title	Live cell imaging of single genomic loci with quantum dot-labeled TALEs
title_short	Live cell imaging of single genomic loci with quantum dot-labeled TALEs
title_full	Live cell imaging of single genomic loci with quantum dot-labeled TALEs
title_fullStr	Live cell imaging of single genomic loci with quantum dot-labeled TALEs
title_full_unstemmed	Live cell imaging of single genomic loci with quantum dot-labeled TALEs
title_sort	live cell imaging of single genomic loci with quantum dot-labeled tales
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/d299f1264a2a475692ab68c7f85c2847
work_keys_str_mv	AT yingxinma livecellimagingofsinglegenomiclociwithquantumdotlabeledtales AT mingxiuwang livecellimagingofsinglegenomiclociwithquantumdotlabeledtales AT weili livecellimagingofsinglegenomiclociwithquantumdotlabeledtales AT zhipingzhang livecellimagingofsinglegenomiclociwithquantumdotlabeledtales AT xiaoweizhang livecellimagingofsinglegenomiclociwithquantumdotlabeledtales AT tianweitan livecellimagingofsinglegenomiclociwithquantumdotlabeledtales AT xianenzhang livecellimagingofsinglegenomiclociwithquantumdotlabeledtales AT zongqiangcui livecellimagingofsinglegenomiclociwithquantumdotlabeledtales
_version_	1718381640625946624

Live cell imaging of single genomic loci with quantum dot-labeled TALEs

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