Foxp3+ regulatory T cells maintain the bone marrow microenvironment for B cell lymphopoiesis

Foxp3+ regulatory T cells maintain the bone marrow microenvironment for B cell lymphopoiesis

Treg cells suppress peripheral immune responses, but their function in haematopoiesis is unclear. Here the authors show they modulate the bone marrow microenvironment to sustain haematopoietic stem cell-driven generation of mature B cells.

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Bibliographic Details
Main Authors: Antonio Pierini, Hidekazu Nishikii, Jeanette Baker, Takaharu Kimura, Hye-Sook Kwon, Yuqiong Pan, Yan Chen, Maite Alvarez, William Strober, Andrea Velardi, Judith A. Shizuru, Joy Y. Wu, Shigeru Chiba, Robert S. Negrin
Format: article
Language:EN
Published: Nature Portfolio 2017
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Science
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Online Access:https://doaj.org/article/d29f840a46334d1d870fa58393c51f4b
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Internet

https://doaj.org/article/d29f840a46334d1d870fa58393c51f4b

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