PQM-1 controls hypoxic survival via regulation of lipid metabolism

Animals respond to hypoxic stress by adjusting metabolic processes to balance survival and reproduction. Here the authors identify the transcription factor PQM-1 as a metabolic regulator that balances hypoxic lipid and carbohydrate metabolism in C. elegans to limit somatic integrity and promote prog...

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Autores principales:	Thomas Heimbucher, Julian Hog, Piyush Gupta, Coleen T. Murphy
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d2a1b5b87ca647a2a6c7a8ab4ed3126e
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spelling	oai:doaj.org-article:d2a1b5b87ca647a2a6c7a8ab4ed3126e2021-12-02T18:51:37ZPQM-1 controls hypoxic survival via regulation of lipid metabolism10.1038/s41467-020-18369-w2041-1723https://doaj.org/article/d2a1b5b87ca647a2a6c7a8ab4ed3126e2020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18369-whttps://doaj.org/toc/2041-1723Animals respond to hypoxic stress by adjusting metabolic processes to balance survival and reproduction. Here the authors identify the transcription factor PQM-1 as a metabolic regulator that balances hypoxic lipid and carbohydrate metabolism in C. elegans to limit somatic integrity and promote progeny survival.Thomas HeimbucherJulian HogPiyush GuptaColeen T. MurphyNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Thomas Heimbucher Julian Hog Piyush Gupta Coleen T. Murphy PQM-1 controls hypoxic survival via regulation of lipid metabolism
description	Animals respond to hypoxic stress by adjusting metabolic processes to balance survival and reproduction. Here the authors identify the transcription factor PQM-1 as a metabolic regulator that balances hypoxic lipid and carbohydrate metabolism in C. elegans to limit somatic integrity and promote progeny survival.
format	article
author	Thomas Heimbucher Julian Hog Piyush Gupta Coleen T. Murphy
author_facet	Thomas Heimbucher Julian Hog Piyush Gupta Coleen T. Murphy
author_sort	Thomas Heimbucher
title	PQM-1 controls hypoxic survival via regulation of lipid metabolism
title_short	PQM-1 controls hypoxic survival via regulation of lipid metabolism
title_full	PQM-1 controls hypoxic survival via regulation of lipid metabolism
title_fullStr	PQM-1 controls hypoxic survival via regulation of lipid metabolism
title_full_unstemmed	PQM-1 controls hypoxic survival via regulation of lipid metabolism
title_sort	pqm-1 controls hypoxic survival via regulation of lipid metabolism
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/d2a1b5b87ca647a2a6c7a8ab4ed3126e
work_keys_str_mv	AT thomasheimbucher pqm1controlshypoxicsurvivalviaregulationoflipidmetabolism AT julianhog pqm1controlshypoxicsurvivalviaregulationoflipidmetabolism AT piyushgupta pqm1controlshypoxicsurvivalviaregulationoflipidmetabolism AT coleentmurphy pqm1controlshypoxicsurvivalviaregulationoflipidmetabolism
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PQM-1 controls hypoxic survival via regulation of lipid metabolism

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