The Balance of Neutrophil Extracellular Trap Formation and Nuclease Degradation: an Unknown Role of Bacterial Coinfections in COVID-19 Patients?

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is leading to public health crises worldwide. An understanding of the pathogenesis and the development of treatment strategies is of high interest. Recently, neutrophil extracellular traps (NETs) have been identified as a potential driver...

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Autores principales: Nicole de Buhr, Maren von Köckritz-Blickwede
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Lenguaje:EN
Publicado: American Society for Microbiology 2021
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spelling oai:doaj.org-article:d2add0f51e4b456a99f77c5da4bb7e562021-11-03T18:15:38ZThe Balance of Neutrophil Extracellular Trap Formation and Nuclease Degradation: an Unknown Role of Bacterial Coinfections in COVID-19 Patients?2161-21292150-751110.1128/mBio.03304-20https://doaj.org/article/d2add0f51e4b456a99f77c5da4bb7e562021-02-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.03304-20https://doaj.org/toc/2161-2129https://doaj.org/toc/2150-7511 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is leading to public health crises worldwide. An understanding of the pathogenesis and the development of treatment strategies is of high interest. Recently, neutrophil extracellular traps (NETs) have been identified as a potential driver of severe SARS-CoV-2 infections in humans. NETs are extracellular DNA fibers released by neutrophils after contact with various stimuli and accumulate antimicrobial substances or host defense peptides.Nicole de BuhrMaren von Köckritz-BlickwedeAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 1 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Nicole de Buhr
Maren von Köckritz-Blickwede
The Balance of Neutrophil Extracellular Trap Formation and Nuclease Degradation: an Unknown Role of Bacterial Coinfections in COVID-19 Patients?
description Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is leading to public health crises worldwide. An understanding of the pathogenesis and the development of treatment strategies is of high interest. Recently, neutrophil extracellular traps (NETs) have been identified as a potential driver of severe SARS-CoV-2 infections in humans. NETs are extracellular DNA fibers released by neutrophils after contact with various stimuli and accumulate antimicrobial substances or host defense peptides.
format article
author Nicole de Buhr
Maren von Köckritz-Blickwede
author_facet Nicole de Buhr
Maren von Köckritz-Blickwede
author_sort Nicole de Buhr
title The Balance of Neutrophil Extracellular Trap Formation and Nuclease Degradation: an Unknown Role of Bacterial Coinfections in COVID-19 Patients?
title_short The Balance of Neutrophil Extracellular Trap Formation and Nuclease Degradation: an Unknown Role of Bacterial Coinfections in COVID-19 Patients?
title_full The Balance of Neutrophil Extracellular Trap Formation and Nuclease Degradation: an Unknown Role of Bacterial Coinfections in COVID-19 Patients?
title_fullStr The Balance of Neutrophil Extracellular Trap Formation and Nuclease Degradation: an Unknown Role of Bacterial Coinfections in COVID-19 Patients?
title_full_unstemmed The Balance of Neutrophil Extracellular Trap Formation and Nuclease Degradation: an Unknown Role of Bacterial Coinfections in COVID-19 Patients?
title_sort balance of neutrophil extracellular trap formation and nuclease degradation: an unknown role of bacterial coinfections in covid-19 patients?
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/d2add0f51e4b456a99f77c5da4bb7e56
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