Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat
Cold-induced activation of thermogenesis in white adipose tissue (WAT), or ‘beiging’, is associated with WAT angiogenesis. Here the authors show that PDGF-CC is secreted from endothelial cells in the context of WAT angiogenesis and its paracrine action on adipocytes contributes to cold-induced beigi...
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Nature Portfolio
2016
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oai:doaj.org-article:d2b7dcc14440407294f031a92cd4d4a92021-12-02T16:57:02ZEndothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat10.1038/ncomms121522041-1723https://doaj.org/article/d2b7dcc14440407294f031a92cd4d4a92016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12152https://doaj.org/toc/2041-1723Cold-induced activation of thermogenesis in white adipose tissue (WAT), or ‘beiging’, is associated with WAT angiogenesis. Here the authors show that PDGF-CC is secreted from endothelial cells in the context of WAT angiogenesis and its paracrine action on adipocytes contributes to cold-induced beiging.Takahiro SekiKayoko HosakaSharon LimCarina FischerJennifer HonekYunlong YangPatrik AnderssonMasaki NakamuraErik NäslundSeppo Ylä-HerttualaMeili SunHideki IwamotoXuri LiYizhi LiuNilesh J. SamaniYihai CaoNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016) |
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Science Q Takahiro Seki Kayoko Hosaka Sharon Lim Carina Fischer Jennifer Honek Yunlong Yang Patrik Andersson Masaki Nakamura Erik Näslund Seppo Ylä-Herttuala Meili Sun Hideki Iwamoto Xuri Li Yizhi Liu Nilesh J. Samani Yihai Cao Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat |
description |
Cold-induced activation of thermogenesis in white adipose tissue (WAT), or ‘beiging’, is associated with WAT angiogenesis. Here the authors show that PDGF-CC is secreted from endothelial cells in the context of WAT angiogenesis and its paracrine action on adipocytes contributes to cold-induced beiging. |
format |
article |
author |
Takahiro Seki Kayoko Hosaka Sharon Lim Carina Fischer Jennifer Honek Yunlong Yang Patrik Andersson Masaki Nakamura Erik Näslund Seppo Ylä-Herttuala Meili Sun Hideki Iwamoto Xuri Li Yizhi Liu Nilesh J. Samani Yihai Cao |
author_facet |
Takahiro Seki Kayoko Hosaka Sharon Lim Carina Fischer Jennifer Honek Yunlong Yang Patrik Andersson Masaki Nakamura Erik Näslund Seppo Ylä-Herttuala Meili Sun Hideki Iwamoto Xuri Li Yizhi Liu Nilesh J. Samani Yihai Cao |
author_sort |
Takahiro Seki |
title |
Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat |
title_short |
Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat |
title_full |
Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat |
title_fullStr |
Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat |
title_full_unstemmed |
Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat |
title_sort |
endothelial pdgf-cc regulates angiogenesis-dependent thermogenesis in beige fat |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/d2b7dcc14440407294f031a92cd4d4a9 |
work_keys_str_mv |
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