Endogenous complement human serum bactericidal assay (enc-hSBA) for vaccine effectiveness assessments against meningococcal serogroup B

Abstract Immunogenicity of vaccines against meningococcal serogroup B (MenB) has been assessed pre-licensure with a human serum bactericidal activity assay (hSBA), tested against small numbers of strains. We report the qualification/validation of an alternative qualitative hSBA which uses endogenous...

Full description

Saved in:
Bibliographic Details
Main Authors: Annett Kleinschmidt, Kumaran Vadivelu, Laura Serino, Nina Neidig, Bertrand de Wergifosse
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Online Access:https://doaj.org/article/d2bbc49e56634308bbf07266dd7e19c1
Tags: Add Tag
No Tags, Be the first to tag this record!