Cellular and physiological circadian mechanisms drive diurnal cell proliferation and expansion of white adipose tissue

During the expansion of adipose tissue adipocyte progenitor cells proliferate and undergo adipogenesis. Here, the authors show that adipocyte progenitor cell proliferation in visceral adipose tissue has a diurnal pattern, which is dependent on both energy intake and the circadian clock.

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Detalles Bibliográficos
Autores principales: Aleix Ribas-Latre, Rafael Bravo Santos, Baharan Fekry, Yomna M. Tamim, Samay Shivshankar, Alaa M. T. Mohamed, Corrine Baumgartner, Christopher Kwok, Claudia Gebhardt, Angielyn Rivera, Zhanguo Gao, Kai Sun, John T. Heiker, Brad E. Snyder, Mikhail G. Kolonin, Kristin L. Eckel-Mahan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/d2bcdacfb8da49f1947d4b6f3b07213c
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Descripción
Sumario:During the expansion of adipose tissue adipocyte progenitor cells proliferate and undergo adipogenesis. Here, the authors show that adipocyte progenitor cell proliferation in visceral adipose tissue has a diurnal pattern, which is dependent on both energy intake and the circadian clock.