Cellular and physiological circadian mechanisms drive diurnal cell proliferation and expansion of white adipose tissue

During the expansion of adipose tissue adipocyte progenitor cells proliferate and undergo adipogenesis. Here, the authors show that adipocyte progenitor cell proliferation in visceral adipose tissue has a diurnal pattern, which is dependent on both energy intake and the circadian clock.

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Autores principales: Aleix Ribas-Latre, Rafael Bravo Santos, Baharan Fekry, Yomna M. Tamim, Samay Shivshankar, Alaa M. T. Mohamed, Corrine Baumgartner, Christopher Kwok, Claudia Gebhardt, Angielyn Rivera, Zhanguo Gao, Kai Sun, John T. Heiker, Brad E. Snyder, Mikhail G. Kolonin, Kristin L. Eckel-Mahan
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/d2bcdacfb8da49f1947d4b6f3b07213c
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spelling oai:doaj.org-article:d2bcdacfb8da49f1947d4b6f3b07213c2021-12-02T17:52:29ZCellular and physiological circadian mechanisms drive diurnal cell proliferation and expansion of white adipose tissue10.1038/s41467-021-23770-02041-1723https://doaj.org/article/d2bcdacfb8da49f1947d4b6f3b07213c2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23770-0https://doaj.org/toc/2041-1723During the expansion of adipose tissue adipocyte progenitor cells proliferate and undergo adipogenesis. Here, the authors show that adipocyte progenitor cell proliferation in visceral adipose tissue has a diurnal pattern, which is dependent on both energy intake and the circadian clock.Aleix Ribas-LatreRafael Bravo SantosBaharan FekryYomna M. TamimSamay ShivshankarAlaa M. T. MohamedCorrine BaumgartnerChristopher KwokClaudia GebhardtAngielyn RiveraZhanguo GaoKai SunJohn T. HeikerBrad E. SnyderMikhail G. KoloninKristin L. Eckel-MahanNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Aleix Ribas-Latre
Rafael Bravo Santos
Baharan Fekry
Yomna M. Tamim
Samay Shivshankar
Alaa M. T. Mohamed
Corrine Baumgartner
Christopher Kwok
Claudia Gebhardt
Angielyn Rivera
Zhanguo Gao
Kai Sun
John T. Heiker
Brad E. Snyder
Mikhail G. Kolonin
Kristin L. Eckel-Mahan
Cellular and physiological circadian mechanisms drive diurnal cell proliferation and expansion of white adipose tissue
description During the expansion of adipose tissue adipocyte progenitor cells proliferate and undergo adipogenesis. Here, the authors show that adipocyte progenitor cell proliferation in visceral adipose tissue has a diurnal pattern, which is dependent on both energy intake and the circadian clock.
format article
author Aleix Ribas-Latre
Rafael Bravo Santos
Baharan Fekry
Yomna M. Tamim
Samay Shivshankar
Alaa M. T. Mohamed
Corrine Baumgartner
Christopher Kwok
Claudia Gebhardt
Angielyn Rivera
Zhanguo Gao
Kai Sun
John T. Heiker
Brad E. Snyder
Mikhail G. Kolonin
Kristin L. Eckel-Mahan
author_facet Aleix Ribas-Latre
Rafael Bravo Santos
Baharan Fekry
Yomna M. Tamim
Samay Shivshankar
Alaa M. T. Mohamed
Corrine Baumgartner
Christopher Kwok
Claudia Gebhardt
Angielyn Rivera
Zhanguo Gao
Kai Sun
John T. Heiker
Brad E. Snyder
Mikhail G. Kolonin
Kristin L. Eckel-Mahan
author_sort Aleix Ribas-Latre
title Cellular and physiological circadian mechanisms drive diurnal cell proliferation and expansion of white adipose tissue
title_short Cellular and physiological circadian mechanisms drive diurnal cell proliferation and expansion of white adipose tissue
title_full Cellular and physiological circadian mechanisms drive diurnal cell proliferation and expansion of white adipose tissue
title_fullStr Cellular and physiological circadian mechanisms drive diurnal cell proliferation and expansion of white adipose tissue
title_full_unstemmed Cellular and physiological circadian mechanisms drive diurnal cell proliferation and expansion of white adipose tissue
title_sort cellular and physiological circadian mechanisms drive diurnal cell proliferation and expansion of white adipose tissue
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/d2bcdacfb8da49f1947d4b6f3b07213c
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