The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development

The cellular and molecular mechanisms regulating hypothalamic patterning and differentiation are unclear. Here, the authors profiled the transcriptome of the developing hypothalamus at single cell level, providing a resource to hypothalamic development in health and disease.

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Detalles Bibliográficos
Autores principales: Dong Won Kim, Parris Whitney Washington, Zoe Qianyi Wang, Sonia Hao Lin, Changyu Sun, Basma Taleb Ismail, Hong Wang, Lizhi Jiang, Seth Blackshaw
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/d2c250613fc248e19cb740b6a764fb62
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Sumario:The cellular and molecular mechanisms regulating hypothalamic patterning and differentiation are unclear. Here, the authors profiled the transcriptome of the developing hypothalamus at single cell level, providing a resource to hypothalamic development in health and disease.