Single-cell normalization and association testing unifying CRISPR screen and gene co-expression analyses with Normalisr
Normalisr removes technical bias in single-cell RNA-seq and detects gene differential and coexpression accurately and efficiently. It also infers gene regulatory and co-expression networks from conventional and CRISPR screen single-cell RNA-seq datasets.
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Nature Portfolio
2021
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oai:doaj.org-article:d2c84d6dbb2441faae25b2f0c72babe52021-11-08T11:11:08ZSingle-cell normalization and association testing unifying CRISPR screen and gene co-expression analyses with Normalisr10.1038/s41467-021-26682-12041-1723https://doaj.org/article/d2c84d6dbb2441faae25b2f0c72babe52021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26682-1https://doaj.org/toc/2041-1723Normalisr removes technical bias in single-cell RNA-seq and detects gene differential and coexpression accurately and efficiently. It also infers gene regulatory and co-expression networks from conventional and CRISPR screen single-cell RNA-seq datasets.Lingfei WangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021) |
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Science Q Lingfei Wang Single-cell normalization and association testing unifying CRISPR screen and gene co-expression analyses with Normalisr |
description |
Normalisr removes technical bias in single-cell RNA-seq and detects gene differential and coexpression accurately and efficiently. It also infers gene regulatory and co-expression networks from conventional and CRISPR screen single-cell RNA-seq datasets. |
format |
article |
author |
Lingfei Wang |
author_facet |
Lingfei Wang |
author_sort |
Lingfei Wang |
title |
Single-cell normalization and association testing unifying CRISPR screen and gene co-expression analyses with Normalisr |
title_short |
Single-cell normalization and association testing unifying CRISPR screen and gene co-expression analyses with Normalisr |
title_full |
Single-cell normalization and association testing unifying CRISPR screen and gene co-expression analyses with Normalisr |
title_fullStr |
Single-cell normalization and association testing unifying CRISPR screen and gene co-expression analyses with Normalisr |
title_full_unstemmed |
Single-cell normalization and association testing unifying CRISPR screen and gene co-expression analyses with Normalisr |
title_sort |
single-cell normalization and association testing unifying crispr screen and gene co-expression analyses with normalisr |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/d2c84d6dbb2441faae25b2f0c72babe5 |
work_keys_str_mv |
AT lingfeiwang singlecellnormalizationandassociationtestingunifyingcrisprscreenandgenecoexpressionanalyseswithnormalisr |
_version_ |
1718442378769989632 |