Single-cell normalization and association testing unifying CRISPR screen and gene co-expression analyses with Normalisr

Normalisr removes technical bias in single-cell RNA-seq and detects gene differential and coexpression accurately and efficiently. It also infers gene regulatory and co-expression networks from conventional and CRISPR screen single-cell RNA-seq datasets.

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Autor principal: Lingfei Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/d2c84d6dbb2441faae25b2f0c72babe5
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spelling oai:doaj.org-article:d2c84d6dbb2441faae25b2f0c72babe52021-11-08T11:11:08ZSingle-cell normalization and association testing unifying CRISPR screen and gene co-expression analyses with Normalisr10.1038/s41467-021-26682-12041-1723https://doaj.org/article/d2c84d6dbb2441faae25b2f0c72babe52021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26682-1https://doaj.org/toc/2041-1723Normalisr removes technical bias in single-cell RNA-seq and detects gene differential and coexpression accurately and efficiently. It also infers gene regulatory and co-expression networks from conventional and CRISPR screen single-cell RNA-seq datasets.Lingfei WangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lingfei Wang
Single-cell normalization and association testing unifying CRISPR screen and gene co-expression analyses with Normalisr
description Normalisr removes technical bias in single-cell RNA-seq and detects gene differential and coexpression accurately and efficiently. It also infers gene regulatory and co-expression networks from conventional and CRISPR screen single-cell RNA-seq datasets.
format article
author Lingfei Wang
author_facet Lingfei Wang
author_sort Lingfei Wang
title Single-cell normalization and association testing unifying CRISPR screen and gene co-expression analyses with Normalisr
title_short Single-cell normalization and association testing unifying CRISPR screen and gene co-expression analyses with Normalisr
title_full Single-cell normalization and association testing unifying CRISPR screen and gene co-expression analyses with Normalisr
title_fullStr Single-cell normalization and association testing unifying CRISPR screen and gene co-expression analyses with Normalisr
title_full_unstemmed Single-cell normalization and association testing unifying CRISPR screen and gene co-expression analyses with Normalisr
title_sort single-cell normalization and association testing unifying crispr screen and gene co-expression analyses with normalisr
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/d2c84d6dbb2441faae25b2f0c72babe5
work_keys_str_mv AT lingfeiwang singlecellnormalizationandassociationtestingunifyingcrisprscreenandgenecoexpressionanalyseswithnormalisr
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