Genetic influences on hub connectivity of the human connectome

Genetic influences on hub connectivity of the human connectome

How genes sculpt the complex architecture of the human connectome remains unclear. Here, the authors show that genes preferentially influence the strength of connectivity between functionally valuable, metabolically costly connections between brain network hubs.

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Auteurs principaux: Aurina Arnatkeviciute, Ben D. Fulcher, Stuart Oldham, Jeggan Tiego, Casey Paquola, Zachary Gerring, Kevin Aquino, Ziarih Hawi, Beth Johnson, Gareth Ball, Marieke Klein, Gustavo Deco, Barbara Franke, Mark A. Bellgrove, Alex Fornito
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Science
Q
Accès en ligne:https://doaj.org/article/d2ca80b7dfdb42b8bba8ca8fcfa0dbfb
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spelling oai:doaj.org-article:d2ca80b7dfdb42b8bba8ca8fcfa0dbfb2021-12-02T16:14:58ZGenetic influences on hub connectivity of the human connectome10.1038/s41467-021-24306-22041-1723https://doaj.org/article/d2ca80b7dfdb42b8bba8ca8fcfa0dbfb2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24306-2https://doaj.org/toc/2041-1723How genes sculpt the complex architecture of the human connectome remains unclear. Here, the authors show that genes preferentially influence the strength of connectivity between functionally valuable, metabolically costly connections between brain network hubs.Aurina ArnatkeviciuteBen D. FulcherStuart OldhamJeggan TiegoCasey PaquolaZachary GerringKevin AquinoZiarih HawiBeth JohnsonGareth BallMarieke KleinGustavo DecoBarbara FrankeMark A. BellgroveAlex FornitoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Aurina Arnatkeviciute
Ben D. Fulcher
Stuart Oldham
Jeggan Tiego
Casey Paquola
Zachary Gerring
Kevin Aquino
Ziarih Hawi
Beth Johnson
Gareth Ball
Marieke Klein
Gustavo Deco
Barbara Franke
Mark A. Bellgrove
Alex Fornito
Genetic influences on hub connectivity of the human connectome
description How genes sculpt the complex architecture of the human connectome remains unclear. Here, the authors show that genes preferentially influence the strength of connectivity between functionally valuable, metabolically costly connections between brain network hubs.
format article
author Aurina Arnatkeviciute
Ben D. Fulcher
Stuart Oldham
Jeggan Tiego
Casey Paquola
Zachary Gerring
Kevin Aquino
Ziarih Hawi
Beth Johnson
Gareth Ball
Marieke Klein
Gustavo Deco
Barbara Franke
Mark A. Bellgrove
Alex Fornito
author_facet Aurina Arnatkeviciute
Ben D. Fulcher
Stuart Oldham
Jeggan Tiego
Casey Paquola
Zachary Gerring
Kevin Aquino
Ziarih Hawi
Beth Johnson
Gareth Ball
Marieke Klein
Gustavo Deco
Barbara Franke
Mark A. Bellgrove
Alex Fornito
author_sort Aurina Arnatkeviciute
title Genetic influences on hub connectivity of the human connectome
title_short Genetic influences on hub connectivity of the human connectome
title_full Genetic influences on hub connectivity of the human connectome
title_fullStr Genetic influences on hub connectivity of the human connectome
title_full_unstemmed Genetic influences on hub connectivity of the human connectome
title_sort genetic influences on hub connectivity of the human connectome
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/d2ca80b7dfdb42b8bba8ca8fcfa0dbfb
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