Risk factors associated with the development of delirium in general ICU patients. A prospective observational study.

<h4>Objective</h4>We aimed to analyze risk factors related to the development of delirium, aiming for early intervention in patients with greater risk.<h4>Material and methods</h4>Observational study, including prospectively collected patients treated in a single general ICU....

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Autores principales:	Beatriz Lobo-Valbuena, Federico Gordo, Ana Abella, Sofía Garcia-Manzanedo, Maria-Mercedes Garcia-Arias, Inés Torrejón, David Varillas-Delgado, Rosario Molina
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/d2cb55fe6b2344da816772cde8a7c24e
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spelling	oai:doaj.org-article:d2cb55fe6b2344da816772cde8a7c24e2021-12-02T20:04:44ZRisk factors associated with the development of delirium in general ICU patients. A prospective observational study.1932-620310.1371/journal.pone.0255522https://doaj.org/article/d2cb55fe6b2344da816772cde8a7c24e2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0255522https://doaj.org/toc/1932-6203<h4>Objective</h4>We aimed to analyze risk factors related to the development of delirium, aiming for early intervention in patients with greater risk.<h4>Material and methods</h4>Observational study, including prospectively collected patients treated in a single general ICU. These were classified into two groups, according to whether they developed delirium or not (screening performed using CAM-ICU tool). Demographics and clinical data were analyzed. Multivariate logistic regression analyses were performed to quantify existing associations.<h4>Results</h4>1462 patients were included. 93 developed delirium (incidence: 6.3%). These were older, scored higher on the Clinical Frailty Scale, on the risk scores on admission (SAPS-3 and SOFA), and had a greater number of organ failures (OF). We observed more incidence of delirium in patients who (a) presented more than two OF (20.4%; OR 4.9; CI95%: 2.9-8.2), and (b) were more than 74 years old albeit having <2 OF (8.6%; OR 2.1; CI95%: 1.3-3.5). Patients who developed delirium had longer ICU and hospital length-of-stays and a higher rate of readmission.<h4>Conclusions</h4>The highest risk observed for developing delirium clustered in patients who presented more than 2 OF and patients over 74 years old. The detection of patients at high risk for developing delirium could imply a change in management and improved quality of care.Beatriz Lobo-ValbuenaFederico GordoAna AbellaSofía Garcia-ManzanedoMaria-Mercedes Garcia-AriasInés TorrejónDavid Varillas-DelgadoRosario MolinaPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 9, p e0255522 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Beatriz Lobo-Valbuena Federico Gordo Ana Abella Sofía Garcia-Manzanedo Maria-Mercedes Garcia-Arias Inés Torrejón David Varillas-Delgado Rosario Molina Risk factors associated with the development of delirium in general ICU patients. A prospective observational study.
description	<h4>Objective</h4>We aimed to analyze risk factors related to the development of delirium, aiming for early intervention in patients with greater risk.<h4>Material and methods</h4>Observational study, including prospectively collected patients treated in a single general ICU. These were classified into two groups, according to whether they developed delirium or not (screening performed using CAM-ICU tool). Demographics and clinical data were analyzed. Multivariate logistic regression analyses were performed to quantify existing associations.<h4>Results</h4>1462 patients were included. 93 developed delirium (incidence: 6.3%). These were older, scored higher on the Clinical Frailty Scale, on the risk scores on admission (SAPS-3 and SOFA), and had a greater number of organ failures (OF). We observed more incidence of delirium in patients who (a) presented more than two OF (20.4%; OR 4.9; CI95%: 2.9-8.2), and (b) were more than 74 years old albeit having <2 OF (8.6%; OR 2.1; CI95%: 1.3-3.5). Patients who developed delirium had longer ICU and hospital length-of-stays and a higher rate of readmission.<h4>Conclusions</h4>The highest risk observed for developing delirium clustered in patients who presented more than 2 OF and patients over 74 years old. The detection of patients at high risk for developing delirium could imply a change in management and improved quality of care.
format	article
author	Beatriz Lobo-Valbuena Federico Gordo Ana Abella Sofía Garcia-Manzanedo Maria-Mercedes Garcia-Arias Inés Torrejón David Varillas-Delgado Rosario Molina
author_facet	Beatriz Lobo-Valbuena Federico Gordo Ana Abella Sofía Garcia-Manzanedo Maria-Mercedes Garcia-Arias Inés Torrejón David Varillas-Delgado Rosario Molina
author_sort	Beatriz Lobo-Valbuena
title	Risk factors associated with the development of delirium in general ICU patients. A prospective observational study.
title_short	Risk factors associated with the development of delirium in general ICU patients. A prospective observational study.
title_full	Risk factors associated with the development of delirium in general ICU patients. A prospective observational study.
title_fullStr	Risk factors associated with the development of delirium in general ICU patients. A prospective observational study.
title_full_unstemmed	Risk factors associated with the development of delirium in general ICU patients. A prospective observational study.
title_sort	risk factors associated with the development of delirium in general icu patients. a prospective observational study.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/d2cb55fe6b2344da816772cde8a7c24e
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Risk factors associated with the development of delirium in general ICU patients. A prospective observational study.

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