Insufficient Acidification of Autophagosomes Facilitates Group A Streptococcus Survival and Growth in Endothelial Cells
ABSTRACT Group A streptococcus (GAS) is an important human pathogen, and its invasion via blood vessels is critically important in serious events such as bacteremia or multiorgan failure. Although GAS was identified as an extracellular bacterium, the internalization of GAS into nonphagocytic cells m...
Saved in:
Main Authors: | Shiou-Ling Lu, Chih-Feng Kuo, Hao-Wen Chen, Yi-Shuan Yang, Ching-Chuan Liu, Robert Anderson, Jiunn-Jong Wu, Yee-Shin Lin |
---|---|
Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2015
|
Subjects: | |
Online Access: | https://doaj.org/article/d2cf2761dfe0408a9c4fd6e9d526e112 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Group A Streptococcus Induces LAPosomes via SLO/β1 Integrin/NOX2/ROS Pathway in Endothelial Cells That Are Ineffective in Bacterial Killing and Suppress Xenophagy
by: Yi-Lin Cheng, et al.
Published: (2019) -
Erratum for Cheng et al., “Group A <italic toggle="yes">Streptococcus</italic> Induces LAPosomes via SLO/β1 Integrin/NOX2/ROS Pathway in Endothelial Cells That Are Ineffective in Bacterial Killing and Suppress Xenophagy”
by: Yi-Lin Cheng, et al.
Published: (2021) -
Galectin-3 Inhibits Galectin-8/Parkin-Mediated Ubiquitination of Group A Streptococcus
by: Yi-Lin Cheng, et al.
Published: (2017) -
Streptolysin O and NAD-Glycohydrolase Prevent Phagolysosome Acidification and Promote Group A <italic toggle="yes">Streptococcus</italic> Survival in Macrophages
by: Benedicte Bastiat-Sempe, et al.
Published: (2014) -
Key Regulators of Autophagosome Closure
by: Wenyan Jiang, et al.
Published: (2021)