Physical activity during pregnancy and association with changes in fat mass and adipokines in women of normal-weight or with obesity

Abstract Adipose tissue and adipokine concentrations change markedly during pregnancy, but the effects of physical activity on these changes are rarely studied. We aimed to assess physical activity levels in pregnant women of normal-weight (NW) or with obesity (OB), and to determine the relation wit...

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Autores principales:	Ulrika Andersson-Hall, Hanna de Maré, Freja Askeli, Mats Börjesson, Agneta Holmäng
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/d2de183fe4374f1887180675148b3d7f
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spelling	oai:doaj.org-article:d2de183fe4374f1887180675148b3d7f2021-12-02T17:23:51ZPhysical activity during pregnancy and association with changes in fat mass and adipokines in women of normal-weight or with obesity10.1038/s41598-021-91980-z2045-2322https://doaj.org/article/d2de183fe4374f1887180675148b3d7f2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-91980-zhttps://doaj.org/toc/2045-2322Abstract Adipose tissue and adipokine concentrations change markedly during pregnancy, but the effects of physical activity on these changes are rarely studied. We aimed to assess physical activity levels in pregnant women of normal-weight (NW) or with obesity (OB), and to determine the relation with changes in fat mass and adipokines. In each trimester, pregnant women (136 NW, 51 OB) were interviewed about their physical activity and had their body composition, leptin, soluble leptin receptor (sOB-R) and adiponectin determined. NW reported higher activity and more aerobic exercise than OB during early pregnancy. Both groups maintained training frequency but reduced overall activity as pregnancy progressed. NW women reporting aerobic and/or resistance exercise and OB women reporting aerobic exercise had greater sOB-R increases (independent of BMI or gestational weight gain). In NW, exercise also associated with lower fat mass and leptin increases. Higher activity levels associated with lower gestational weight gain in both groups. The relationship between physical activity and adiponectin differed between NW and OB. Maternal exercise may partly mediate its beneficial effects through regulation of leptin bioavailability, by enhancing pregnancy-induced increases in sOB-R. This could be of particular importance in OB with pre-gestational hyperleptinemia and leptin resistance.Ulrika Andersson-HallHanna de MaréFreja AskeliMats BörjessonAgneta HolmängNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ulrika Andersson-Hall Hanna de Maré Freja Askeli Mats Börjesson Agneta Holmäng Physical activity during pregnancy and association with changes in fat mass and adipokines in women of normal-weight or with obesity
description	Abstract Adipose tissue and adipokine concentrations change markedly during pregnancy, but the effects of physical activity on these changes are rarely studied. We aimed to assess physical activity levels in pregnant women of normal-weight (NW) or with obesity (OB), and to determine the relation with changes in fat mass and adipokines. In each trimester, pregnant women (136 NW, 51 OB) were interviewed about their physical activity and had their body composition, leptin, soluble leptin receptor (sOB-R) and adiponectin determined. NW reported higher activity and more aerobic exercise than OB during early pregnancy. Both groups maintained training frequency but reduced overall activity as pregnancy progressed. NW women reporting aerobic and/or resistance exercise and OB women reporting aerobic exercise had greater sOB-R increases (independent of BMI or gestational weight gain). In NW, exercise also associated with lower fat mass and leptin increases. Higher activity levels associated with lower gestational weight gain in both groups. The relationship between physical activity and adiponectin differed between NW and OB. Maternal exercise may partly mediate its beneficial effects through regulation of leptin bioavailability, by enhancing pregnancy-induced increases in sOB-R. This could be of particular importance in OB with pre-gestational hyperleptinemia and leptin resistance.
format	article
author	Ulrika Andersson-Hall Hanna de Maré Freja Askeli Mats Börjesson Agneta Holmäng
author_facet	Ulrika Andersson-Hall Hanna de Maré Freja Askeli Mats Börjesson Agneta Holmäng
author_sort	Ulrika Andersson-Hall
title	Physical activity during pregnancy and association with changes in fat mass and adipokines in women of normal-weight or with obesity
title_short	Physical activity during pregnancy and association with changes in fat mass and adipokines in women of normal-weight or with obesity
title_full	Physical activity during pregnancy and association with changes in fat mass and adipokines in women of normal-weight or with obesity
title_fullStr	Physical activity during pregnancy and association with changes in fat mass and adipokines in women of normal-weight or with obesity
title_full_unstemmed	Physical activity during pregnancy and association with changes in fat mass and adipokines in women of normal-weight or with obesity
title_sort	physical activity during pregnancy and association with changes in fat mass and adipokines in women of normal-weight or with obesity
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d2de183fe4374f1887180675148b3d7f
work_keys_str_mv	AT ulrikaanderssonhall physicalactivityduringpregnancyandassociationwithchangesinfatmassandadipokinesinwomenofnormalweightorwithobesity AT hannademare physicalactivityduringpregnancyandassociationwithchangesinfatmassandadipokinesinwomenofnormalweightorwithobesity AT frejaaskeli physicalactivityduringpregnancyandassociationwithchangesinfatmassandadipokinesinwomenofnormalweightorwithobesity AT matsborjesson physicalactivityduringpregnancyandassociationwithchangesinfatmassandadipokinesinwomenofnormalweightorwithobesity AT agnetaholmang physicalactivityduringpregnancyandassociationwithchangesinfatmassandadipokinesinwomenofnormalweightorwithobesity
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Physical activity during pregnancy and association with changes in fat mass and adipokines in women of normal-weight or with obesity

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