The novel Mas agonist, CGEN-856S, attenuates isoproterenol-induced cardiac remodeling and myocardial infarction injury in rats.

The novel Mas agonist, CGEN-856S, attenuates isoproterenol-induced cardiac remodeling and myocardial infarction injury in rats.

CGEN-856S is a novel Mas agonist. Herein, we examined the effects of this peptide on isoproterenol (ISO)-induced cardiac remodeling and myocardial infarction (MI) injury. We also sought to determine whether CGEN-856S activates the underlying mechanisms related to Mas receptor activation. Heart hyper...

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Main Authors: Sílvia Q Savergnini, Danielle Ianzer, Mariana B L Carvalho, Anderson J Ferreira, Gerluza A B Silva, Fúlvia D Marques, Antônio Augusto B Peluso, Merav Beiman, Gady Cojocaru, Yossi Cohen, Alvair P Almeida, Galit Rotman, Robson A S Santos
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/d2e285fefedf48dba9ca087fbd190ae1
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https://doaj.org/article/d2e285fefedf48dba9ca087fbd190ae1

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