Epilepsy in Older People in Sub-Saharan Africa: A Systematic Review

Felix Bongomin,1,2 Elly Katabira,1 Martha Sajatovic,3 Mark Kaddumukasa1 1Department of Medicine, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda; 2Department of Medical Microbiology & Immunology, Faculty of Medicine, Gulu University, Gulu, Uganda; 3Neurologic...

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Autores principales:	Bongomin F, Katabira E, Sajatovic M, Kaddumukasa M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	seizure epilepsy elderly persons sub-saharan africa Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/d2e69937456c4c8f965c492b2622acf8
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spelling	oai:doaj.org-article:d2e69937456c4c8f965c492b2622acf82021-12-02T16:12:37ZEpilepsy in Older People in Sub-Saharan Africa: A Systematic Review1178-2021https://doaj.org/article/d2e69937456c4c8f965c492b2622acf82021-07-01T00:00:00Zhttps://www.dovepress.com/epilepsy-in-older-people-in-sub-saharan-africa-a-systematic-review-peer-reviewed-fulltext-article-NDThttps://doaj.org/toc/1178-2021Felix Bongomin,1,2 Elly Katabira,1 Martha Sajatovic,3 Mark Kaddumukasa1 1Department of Medicine, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda; 2Department of Medical Microbiology & Immunology, Faculty of Medicine, Gulu University, Gulu, Uganda; 3Neurological and Behavioral Outcomes Center, University Hospitals Cleveland Medical Center & Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USACorrespondence: Felix BongominDepartment of Medical Microbiology & Immunology, Faculty of Medicine, Gulu University, P.O. Box 166, Gulu, UgandaEmail drbongomin@gmail.comBackground: Over one-fourth of new onset epilepsy occurs after age 60. However, the burden of epilepsy and other seizure disorders among this special population in Africa is largely unknown, despite a growingnumber of elderly persons on the continent. This study aimed to assess the prevalence and risk factors for epilepsy among persons aged 60 years or older in Africa.Methods: We conducted a systematic review by searching MEDLINE (via) and EMBASE databases from inception to 30th October 2020. Primary researches reporting prevalence or incidence of seizures or epilepsy in older persons (≥ 60 years) were included. Review articles were excluded.Results: We retrieved 107 citations from which 4 studies, recruiting 10, 334 participants were eligible. The studies were conducted between 1999 and 2018 and published between 2005 and 2019. Two of the studies were conducted in the West African countries of Niger and Senegal; meanwhile, the remaining 2 were conducted in East African country of Tanzania. Regarding study design, three were either hospital-based or community-based cross-sectional studies. Meanwhile, 1 was a retrospective hospital-based study. Of the 10,334 participants, 81 (0.78%) had a seizure disorder. The prevalence of seizure ranged from 0.02% to 3.2%.Conclusion: There are limited data on the prevalence of epilepsy in older persons in older adults in most countries in sub-Saharan Africa. Epilepsy among the older adults remains a challenge in Africa and more information is needed to understand the burden to improve care.Keywords: seizure, epilepsy, elderly persons, sub-Saharan AfricaBongomin FKatabira ESajatovic MKaddumukasa MDove Medical Pressarticleseizureepilepsyelderly personssub-saharan africaNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 17, Pp 2309-2314 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	seizure epilepsy elderly persons sub-saharan africa Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	seizure epilepsy elderly persons sub-saharan africa Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Bongomin F Katabira E Sajatovic M Kaddumukasa M Epilepsy in Older People in Sub-Saharan Africa: A Systematic Review
description	Felix Bongomin,1,2 Elly Katabira,1 Martha Sajatovic,3 Mark Kaddumukasa1 1Department of Medicine, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda; 2Department of Medical Microbiology & Immunology, Faculty of Medicine, Gulu University, Gulu, Uganda; 3Neurological and Behavioral Outcomes Center, University Hospitals Cleveland Medical Center & Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USACorrespondence: Felix BongominDepartment of Medical Microbiology & Immunology, Faculty of Medicine, Gulu University, P.O. Box 166, Gulu, UgandaEmail drbongomin@gmail.comBackground: Over one-fourth of new onset epilepsy occurs after age 60. However, the burden of epilepsy and other seizure disorders among this special population in Africa is largely unknown, despite a growingnumber of elderly persons on the continent. This study aimed to assess the prevalence and risk factors for epilepsy among persons aged 60 years or older in Africa.Methods: We conducted a systematic review by searching MEDLINE (via) and EMBASE databases from inception to 30th October 2020. Primary researches reporting prevalence or incidence of seizures or epilepsy in older persons (≥ 60 years) were included. Review articles were excluded.Results: We retrieved 107 citations from which 4 studies, recruiting 10, 334 participants were eligible. The studies were conducted between 1999 and 2018 and published between 2005 and 2019. Two of the studies were conducted in the West African countries of Niger and Senegal; meanwhile, the remaining 2 were conducted in East African country of Tanzania. Regarding study design, three were either hospital-based or community-based cross-sectional studies. Meanwhile, 1 was a retrospective hospital-based study. Of the 10,334 participants, 81 (0.78%) had a seizure disorder. The prevalence of seizure ranged from 0.02% to 3.2%.Conclusion: There are limited data on the prevalence of epilepsy in older persons in older adults in most countries in sub-Saharan Africa. Epilepsy among the older adults remains a challenge in Africa and more information is needed to understand the burden to improve care.Keywords: seizure, epilepsy, elderly persons, sub-Saharan Africa
format	article
author	Bongomin F Katabira E Sajatovic M Kaddumukasa M
author_facet	Bongomin F Katabira E Sajatovic M Kaddumukasa M
author_sort	Bongomin F
title	Epilepsy in Older People in Sub-Saharan Africa: A Systematic Review
title_short	Epilepsy in Older People in Sub-Saharan Africa: A Systematic Review
title_full	Epilepsy in Older People in Sub-Saharan Africa: A Systematic Review
title_fullStr	Epilepsy in Older People in Sub-Saharan Africa: A Systematic Review
title_full_unstemmed	Epilepsy in Older People in Sub-Saharan Africa: A Systematic Review
title_sort	epilepsy in older people in sub-saharan africa: a systematic review
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/d2e69937456c4c8f965c492b2622acf8
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Epilepsy in Older People in Sub-Saharan Africa: A Systematic Review

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