Metastatic Alveolar Rhabdomyosarcoma with Extensive Bone Marrow Replacement in an Older Adult

Rhabdomyosarcoma is extremely rare in adults. Metastatic rhabdomyosarcoma can resemble other malignancies, which can delay diagnosis and prompt treatment. This case illustrates an example of metastatic alveolar rhabdomyosarcoma with concurrent bone marrow infiltration. A 67-year-old woman presented...

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Autores principales:	Justin J. Cheng, Ryan T. Mott, Paul D. Savage, Ravi K. Paluri
Formato:	article
Lenguaje:	EN
Publicado:	Karger Publishers 2021
Materias:	rhabdomyosarcoma thrombocytopenia bone marrow Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/d2ee85aa1cf84efb8a1ab7687d1be5da
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spelling	oai:doaj.org-article:d2ee85aa1cf84efb8a1ab7687d1be5da2021-11-18T11:08:46ZMetastatic Alveolar Rhabdomyosarcoma with Extensive Bone Marrow Replacement in an Older Adult1662-657510.1159/000519595https://doaj.org/article/d2ee85aa1cf84efb8a1ab7687d1be5da2021-10-01T00:00:00Zhttps://www.karger.com/Article/FullText/519595https://doaj.org/toc/1662-6575Rhabdomyosarcoma is extremely rare in adults. Metastatic rhabdomyosarcoma can resemble other malignancies, which can delay diagnosis and prompt treatment. This case illustrates an example of metastatic alveolar rhabdomyosarcoma with concurrent bone marrow infiltration. A 67-year-old woman presented with epistaxis and diffuse bone pain. She developed progressive thrombocytopenia requiring platelet transfusions. The patient was initially thought to have leukemia. She was found to have a large sinonasal mass with extensive metastatic disease and bone marrow infiltration. The patient was ultimately diagnosed with metastatic alveolar rhabdomyosarcoma. She was started on chemotherapy with vincristine, actinomycin, and cyclophosphamide. Unfortunately, she died prior to discharge home. Alveolar rhabdomyosarcoma can resemble a primary bone marrow malignancy when it infiltrates the bone marrow. Further investigation is needed to clarify its clinical behavior and expedite diagnosis and treatment.Justin J. ChengRyan T. MottPaul D. SavageRavi K. PaluriKarger Publishersarticlerhabdomyosarcomathrombocytopeniabone marrowNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENCase Reports in Oncology, Vol 14, Iss 3, Pp 1505-1510 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	rhabdomyosarcoma thrombocytopenia bone marrow Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	rhabdomyosarcoma thrombocytopenia bone marrow Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Justin J. Cheng Ryan T. Mott Paul D. Savage Ravi K. Paluri Metastatic Alveolar Rhabdomyosarcoma with Extensive Bone Marrow Replacement in an Older Adult
description	Rhabdomyosarcoma is extremely rare in adults. Metastatic rhabdomyosarcoma can resemble other malignancies, which can delay diagnosis and prompt treatment. This case illustrates an example of metastatic alveolar rhabdomyosarcoma with concurrent bone marrow infiltration. A 67-year-old woman presented with epistaxis and diffuse bone pain. She developed progressive thrombocytopenia requiring platelet transfusions. The patient was initially thought to have leukemia. She was found to have a large sinonasal mass with extensive metastatic disease and bone marrow infiltration. The patient was ultimately diagnosed with metastatic alveolar rhabdomyosarcoma. She was started on chemotherapy with vincristine, actinomycin, and cyclophosphamide. Unfortunately, she died prior to discharge home. Alveolar rhabdomyosarcoma can resemble a primary bone marrow malignancy when it infiltrates the bone marrow. Further investigation is needed to clarify its clinical behavior and expedite diagnosis and treatment.
format	article
author	Justin J. Cheng Ryan T. Mott Paul D. Savage Ravi K. Paluri
author_facet	Justin J. Cheng Ryan T. Mott Paul D. Savage Ravi K. Paluri
author_sort	Justin J. Cheng
title	Metastatic Alveolar Rhabdomyosarcoma with Extensive Bone Marrow Replacement in an Older Adult
title_short	Metastatic Alveolar Rhabdomyosarcoma with Extensive Bone Marrow Replacement in an Older Adult
title_full	Metastatic Alveolar Rhabdomyosarcoma with Extensive Bone Marrow Replacement in an Older Adult
title_fullStr	Metastatic Alveolar Rhabdomyosarcoma with Extensive Bone Marrow Replacement in an Older Adult
title_full_unstemmed	Metastatic Alveolar Rhabdomyosarcoma with Extensive Bone Marrow Replacement in an Older Adult
title_sort	metastatic alveolar rhabdomyosarcoma with extensive bone marrow replacement in an older adult
publisher	Karger Publishers
publishDate	2021
url	https://doaj.org/article/d2ee85aa1cf84efb8a1ab7687d1be5da
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Metastatic Alveolar Rhabdomyosarcoma with Extensive Bone Marrow Replacement in an Older Adult

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