STUDY OF EFFICACY OF HYPOFRACTIONATED RADIOTHERAPY 8 GRAY IN SINGLE FRACTION IN PALLIATION OF PAIN SECONDARY TO BONE METASTASIS

Objectives: To determine the efficacy of hypo-fractionated radiotherapy 8 Gray in 1 fraction for palliation of pain secondary to bone metastasis. Study Design: Quasi-experimental study. Place and Duration of Study: Oncology department, Combined Military Hospital, Rawalpindi, Sep 2012 to Nov 2013...

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Autores principales:	Usman Ali, Salman Arif, Talha Maqsood, Saira Ahmed, Najia Ahmed, Zeeshan Alvi
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2018
Materias:	bone metastasis palliative Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/d2f2daee3b484962b7896ec96c47eb67
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spelling	oai:doaj.org-article:d2f2daee3b484962b7896ec96c47eb672021-12-03T06:28:07ZSTUDY OF EFFICACY OF HYPOFRACTIONATED RADIOTHERAPY 8 GRAY IN SINGLE FRACTION IN PALLIATION OF PAIN SECONDARY TO BONE METASTASIS0030-96482411-8842https://doaj.org/article/d2f2daee3b484962b7896ec96c47eb672018-10-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/2346/2032https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objectives: To determine the efficacy of hypo-fractionated radiotherapy 8 Gray in 1 fraction for palliation of pain secondary to bone metastasis. Study Design: Quasi-experimental study. Place and Duration of Study: Oncology department, Combined Military Hospital, Rawalpindi, Sep 2012 to Nov 2013. Patients and Methods: Forty three patients were included after permission from concerned authorities and Hospital Ethical Committee. OPD registration numbers, name, age, gender, Eastern Cooperative Oncology Group (ECOG) performance status (PS), diagnosis of primary malignancy along with histopathology and sites of skeletal metastasis were recorded. Radiotherapy 8 Gy in 1 fraction was administered using 6MV (mega voltage) Primus Linear Accelerator with 2-2.5 cm margin around the gross disease at the Oncology department, CMH Rawalpindi. Pain score was recorded using visual analogue scale on the day of administering radiotherapy (day 0) and thirty days (day 30) after radiotherapy to assess response to treatment. Results: There was a statistically significant (<0.001) improvement in the scores of pain with treatment at day 30. Thirty four out of forty three patients (86%) showed an improvement in pain score. Conclusion: Based on our results hypofractionated radiotherapy 8 Gy in 1fraction is an effective modality in the palliation of pain secondary to bone metastasis.Usman AliSalman ArifTalha MaqsoodSaira AhmedNajia AhmedZeeshan AlviArmy Medical College Rawalpindiarticlebone metastasispalliativeMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 68, Iss 5, Pp 1449-1452 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	bone metastasis palliative Medicine R Medicine (General) R5-920
spellingShingle	bone metastasis palliative Medicine R Medicine (General) R5-920 Usman Ali Salman Arif Talha Maqsood Saira Ahmed Najia Ahmed Zeeshan Alvi STUDY OF EFFICACY OF HYPOFRACTIONATED RADIOTHERAPY 8 GRAY IN SINGLE FRACTION IN PALLIATION OF PAIN SECONDARY TO BONE METASTASIS
description	Objectives: To determine the efficacy of hypo-fractionated radiotherapy 8 Gray in 1 fraction for palliation of pain secondary to bone metastasis. Study Design: Quasi-experimental study. Place and Duration of Study: Oncology department, Combined Military Hospital, Rawalpindi, Sep 2012 to Nov 2013. Patients and Methods: Forty three patients were included after permission from concerned authorities and Hospital Ethical Committee. OPD registration numbers, name, age, gender, Eastern Cooperative Oncology Group (ECOG) performance status (PS), diagnosis of primary malignancy along with histopathology and sites of skeletal metastasis were recorded. Radiotherapy 8 Gy in 1 fraction was administered using 6MV (mega voltage) Primus Linear Accelerator with 2-2.5 cm margin around the gross disease at the Oncology department, CMH Rawalpindi. Pain score was recorded using visual analogue scale on the day of administering radiotherapy (day 0) and thirty days (day 30) after radiotherapy to assess response to treatment. Results: There was a statistically significant (<0.001) improvement in the scores of pain with treatment at day 30. Thirty four out of forty three patients (86%) showed an improvement in pain score. Conclusion: Based on our results hypofractionated radiotherapy 8 Gy in 1fraction is an effective modality in the palliation of pain secondary to bone metastasis.
format	article
author	Usman Ali Salman Arif Talha Maqsood Saira Ahmed Najia Ahmed Zeeshan Alvi
author_facet	Usman Ali Salman Arif Talha Maqsood Saira Ahmed Najia Ahmed Zeeshan Alvi
author_sort	Usman Ali
title	STUDY OF EFFICACY OF HYPOFRACTIONATED RADIOTHERAPY 8 GRAY IN SINGLE FRACTION IN PALLIATION OF PAIN SECONDARY TO BONE METASTASIS
title_short	STUDY OF EFFICACY OF HYPOFRACTIONATED RADIOTHERAPY 8 GRAY IN SINGLE FRACTION IN PALLIATION OF PAIN SECONDARY TO BONE METASTASIS
title_full	STUDY OF EFFICACY OF HYPOFRACTIONATED RADIOTHERAPY 8 GRAY IN SINGLE FRACTION IN PALLIATION OF PAIN SECONDARY TO BONE METASTASIS
title_fullStr	STUDY OF EFFICACY OF HYPOFRACTIONATED RADIOTHERAPY 8 GRAY IN SINGLE FRACTION IN PALLIATION OF PAIN SECONDARY TO BONE METASTASIS
title_full_unstemmed	STUDY OF EFFICACY OF HYPOFRACTIONATED RADIOTHERAPY 8 GRAY IN SINGLE FRACTION IN PALLIATION OF PAIN SECONDARY TO BONE METASTASIS
title_sort	study of efficacy of hypofractionated radiotherapy 8 gray in single fraction in palliation of pain secondary to bone metastasis
publisher	Army Medical College Rawalpindi
publishDate	2018
url	https://doaj.org/article/d2f2daee3b484962b7896ec96c47eb67
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STUDY OF EFFICACY OF HYPOFRACTIONATED RADIOTHERAPY 8 GRAY IN SINGLE FRACTION IN PALLIATION OF PAIN SECONDARY TO BONE METASTASIS

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