Bioresorbable vascular scaffolds technology: current use and future developments

Giuseppe Giacchi, Luis Ortega-Paz, Salvatore Brugaletta, Kohki Ishida, Manel Sabaté Cardiology Department, Clinic Cardiovascular Institute, Hospital Clinic, August Pi and Sunyer Biomedical Research Institute (IDIBAPS), University of Barcelona, Barcelona...

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Autores principales:	Giacchi G, Ortega-Paz L, Brugaletta S, Ishida K, Sabaté M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	Absorb GT1 Absorb BVS bioresorbable vascular scaffold BRS coronary scaffold Medical technology R855-855.5
Acceso en línea:	https://doaj.org/article/d30d6010e781453dbfdb71268e7997f0
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spelling	oai:doaj.org-article:d30d6010e781453dbfdb71268e7997f02021-12-02T03:15:29ZBioresorbable vascular scaffolds technology: current use and future developments1179-1470https://doaj.org/article/d30d6010e781453dbfdb71268e7997f02016-07-01T00:00:00Zhttps://www.dovepress.com/bioresorbable-vascular-scaffolds-technology-current-use-and-future-dev-peer-reviewed-article-MDERhttps://doaj.org/toc/1179-1470Giuseppe Giacchi, Luis Ortega-Paz, Salvatore Brugaletta, Kohki Ishida, Manel Sabaté Cardiology Department, Clinic Cardiovascular Institute, Hospital Clinic, August Pi and Sunyer Biomedical Research Institute (IDIBAPS), University of Barcelona, Barcelona, Spain Abstract: Coronary bioresorbable vascular scaffolds are a new appealing therapeutic option in interventional cardiology. The most used and studied is currently the Absorb BVS™. Its backbone is made of poly-l-lactide and coated by a thin layer of poly-d,l-lactide, it releases everolimus and is fully degraded to H2O and CO2 in 2–3 years. Absorb BVS™ seems to offer several theoretical advantages over metallic stent, as it gives temporary mechanical support to vessel wall without permanently caging it. Therefore, long-term endothelial function and structure are not affected. A possible future surgical revascularization is not compromised. Natural vasomotion in response to external stimuli is also recovered. Several observational and randomized trials have been published about BVS clinical outcomes. The main aim of this review is to carry out a systematic analysis about Absorb BVS™ studies, evaluating also the technical improvements of the Absorb GT1 BVS™. Keywords: Absorb GT1, Absorb BVS™, bioresorbable vascular scaffold, BRS, coronary scaffoldGiacchi GOrtega-Paz LBrugaletta SIshida KSabaté MDove Medical PressarticleAbsorb GT1Absorb BVSbioresorbable vascular scaffoldBRScoronary scaffoldMedical technologyR855-855.5ENMedical Devices: Evidence and Research, Vol 2016, Iss Issue 1, Pp 185-198 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Absorb GT1 Absorb BVS bioresorbable vascular scaffold BRS coronary scaffold Medical technology R855-855.5
spellingShingle	Absorb GT1 Absorb BVS bioresorbable vascular scaffold BRS coronary scaffold Medical technology R855-855.5 Giacchi G Ortega-Paz L Brugaletta S Ishida K Sabaté M Bioresorbable vascular scaffolds technology: current use and future developments
description	Giuseppe Giacchi, Luis Ortega-Paz, Salvatore Brugaletta, Kohki Ishida, Manel Sabaté Cardiology Department, Clinic Cardiovascular Institute, Hospital Clinic, August Pi and Sunyer Biomedical Research Institute (IDIBAPS), University of Barcelona, Barcelona, Spain Abstract: Coronary bioresorbable vascular scaffolds are a new appealing therapeutic option in interventional cardiology. The most used and studied is currently the Absorb BVS™. Its backbone is made of poly-l-lactide and coated by a thin layer of poly-d,l-lactide, it releases everolimus and is fully degraded to H2O and CO2 in 2–3 years. Absorb BVS™ seems to offer several theoretical advantages over metallic stent, as it gives temporary mechanical support to vessel wall without permanently caging it. Therefore, long-term endothelial function and structure are not affected. A possible future surgical revascularization is not compromised. Natural vasomotion in response to external stimuli is also recovered. Several observational and randomized trials have been published about BVS clinical outcomes. The main aim of this review is to carry out a systematic analysis about Absorb BVS™ studies, evaluating also the technical improvements of the Absorb GT1 BVS™. Keywords: Absorb GT1, Absorb BVS™, bioresorbable vascular scaffold, BRS, coronary scaffold
format	article
author	Giacchi G Ortega-Paz L Brugaletta S Ishida K Sabaté M
author_facet	Giacchi G Ortega-Paz L Brugaletta S Ishida K Sabaté M
author_sort	Giacchi G
title	Bioresorbable vascular scaffolds technology: current use and future developments
title_short	Bioresorbable vascular scaffolds technology: current use and future developments
title_full	Bioresorbable vascular scaffolds technology: current use and future developments
title_fullStr	Bioresorbable vascular scaffolds technology: current use and future developments
title_full_unstemmed	Bioresorbable vascular scaffolds technology: current use and future developments
title_sort	bioresorbable vascular scaffolds technology: current use and future developments
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/d30d6010e781453dbfdb71268e7997f0
work_keys_str_mv	AT giacchig bioresorbablevascularscaffoldstechnologycurrentuseandfuturedevelopments AT ortegapazl bioresorbablevascularscaffoldstechnologycurrentuseandfuturedevelopments AT brugalettas bioresorbablevascularscaffoldstechnologycurrentuseandfuturedevelopments AT ishidak bioresorbablevascularscaffoldstechnologycurrentuseandfuturedevelopments AT sabatem bioresorbablevascularscaffoldstechnologycurrentuseandfuturedevelopments
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Bioresorbable vascular scaffolds technology: current use and future developments

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