Calcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of NOD2 ligands in macrophages

Macropinocytosis can be induced in several cell types by growth factors to promote nutrient acquisition. Here the authors find that constitutive macropinocytosis, unique to dendritic cells and macrophages, requires the activity of calcium-sensing receptors.

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Autores principales:	Johnathan Canton, Daniel Schlam, Christian Breuer, Michael Gütschow, Michael Glogauer, Sergio Grinstein
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d310334c7e914aec8e88469bb2d97315
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spelling	oai:doaj.org-article:d310334c7e914aec8e88469bb2d973152021-12-02T16:57:04ZCalcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of NOD2 ligands in macrophages10.1038/ncomms112842041-1723https://doaj.org/article/d310334c7e914aec8e88469bb2d973152016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11284https://doaj.org/toc/2041-1723Macropinocytosis can be induced in several cell types by growth factors to promote nutrient acquisition. Here the authors find that constitutive macropinocytosis, unique to dendritic cells and macrophages, requires the activity of calcium-sensing receptors.Johnathan CantonDaniel SchlamChristian BreuerMichael GütschowMichael GlogauerSergio GrinsteinNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Johnathan Canton Daniel Schlam Christian Breuer Michael Gütschow Michael Glogauer Sergio Grinstein Calcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of NOD2 ligands in macrophages
description	Macropinocytosis can be induced in several cell types by growth factors to promote nutrient acquisition. Here the authors find that constitutive macropinocytosis, unique to dendritic cells and macrophages, requires the activity of calcium-sensing receptors.
format	article
author	Johnathan Canton Daniel Schlam Christian Breuer Michael Gütschow Michael Glogauer Sergio Grinstein
author_facet	Johnathan Canton Daniel Schlam Christian Breuer Michael Gütschow Michael Glogauer Sergio Grinstein
author_sort	Johnathan Canton
title	Calcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of NOD2 ligands in macrophages
title_short	Calcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of NOD2 ligands in macrophages
title_full	Calcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of NOD2 ligands in macrophages
title_fullStr	Calcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of NOD2 ligands in macrophages
title_full_unstemmed	Calcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of NOD2 ligands in macrophages
title_sort	calcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of nod2 ligands in macrophages
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/d310334c7e914aec8e88469bb2d97315
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Calcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of NOD2 ligands in macrophages

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