Identification and characterization of B-cell epitopes in the DBL4ε domain of VAR2CSA.

Identification and characterization of B-cell epitopes in the DBL4ε domain of VAR2CSA.

Malaria during pregnancy in Plasmodium falciparum endemic regions is a major cause of mortality and severe morbidity. VAR2CSA is the parasite ligand responsible for sequestration of Plasmodium falciparum infected erythrocytes to the receptor chondroitin sulfate A (CSA) in the placenta and is the lea...

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Autores principales: Sisse B Ditlev, Morten A Nielsen, Mafalda Resende, Mette Ø Agerbæk, Vera V Pinto, Pernille H Andersen, Pamela Magistrado, John Lusingu, Madeleine Dahlbäck, Thor G Theander, Ali Salanti
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/d31c030318954055ab7881c7b7595b85
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