Chromosome compartments on the inactive X guide TAD formation independently of transcription during X-reactivation

Both A/B compartments and TADs are thought to be absent from the inactive X chromosome, but to be re-established with transcriptional reactivation and chromatin opening during X-reactivation. Here, the authors characterise gene reactivation, chromatin opening and chromosome topology during X-reactiv...

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Autores principales:	Moritz Bauer, Enrique Vidal, Eduard Zorita, Nil Üresin, Stefan F. Pinter, Guillaume J. Filion, Bernhard Payer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d32434f601f34898a745cb1caef82c09
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spelling	oai:doaj.org-article:d32434f601f34898a745cb1caef82c092021-12-02T17:52:19ZChromosome compartments on the inactive X guide TAD formation independently of transcription during X-reactivation10.1038/s41467-021-23610-12041-1723https://doaj.org/article/d32434f601f34898a745cb1caef82c092021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23610-1https://doaj.org/toc/2041-1723Both A/B compartments and TADs are thought to be absent from the inactive X chromosome, but to be re-established with transcriptional reactivation and chromatin opening during X-reactivation. Here, the authors characterise gene reactivation, chromatin opening and chromosome topology during X-reactivation, observe A/B-like compartments on the inactive X that guide TAD formation independently of transcription during X-reactivation.Moritz BauerEnrique VidalEduard ZoritaNil ÜresinStefan F. PinterGuillaume J. FilionBernhard PayerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Moritz Bauer Enrique Vidal Eduard Zorita Nil Üresin Stefan F. Pinter Guillaume J. Filion Bernhard Payer Chromosome compartments on the inactive X guide TAD formation independently of transcription during X-reactivation
description	Both A/B compartments and TADs are thought to be absent from the inactive X chromosome, but to be re-established with transcriptional reactivation and chromatin opening during X-reactivation. Here, the authors characterise gene reactivation, chromatin opening and chromosome topology during X-reactivation, observe A/B-like compartments on the inactive X that guide TAD formation independently of transcription during X-reactivation.
format	article
author	Moritz Bauer Enrique Vidal Eduard Zorita Nil Üresin Stefan F. Pinter Guillaume J. Filion Bernhard Payer
author_facet	Moritz Bauer Enrique Vidal Eduard Zorita Nil Üresin Stefan F. Pinter Guillaume J. Filion Bernhard Payer
author_sort	Moritz Bauer
title	Chromosome compartments on the inactive X guide TAD formation independently of transcription during X-reactivation
title_short	Chromosome compartments on the inactive X guide TAD formation independently of transcription during X-reactivation
title_full	Chromosome compartments on the inactive X guide TAD formation independently of transcription during X-reactivation
title_fullStr	Chromosome compartments on the inactive X guide TAD formation independently of transcription during X-reactivation
title_full_unstemmed	Chromosome compartments on the inactive X guide TAD formation independently of transcription during X-reactivation
title_sort	chromosome compartments on the inactive x guide tad formation independently of transcription during x-reactivation
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d32434f601f34898a745cb1caef82c09
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Chromosome compartments on the inactive X guide TAD formation independently of transcription during X-reactivation

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