Chromosome compartments on the inactive X guide TAD formation independently of transcription during X-reactivation

Both A/B compartments and TADs are thought to be absent from the inactive X chromosome, but to be re-established with transcriptional reactivation and chromatin opening during X-reactivation. Here, the authors characterise gene reactivation, chromatin opening and chromosome topology during X-reactiv...

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Autores principales: Moritz Bauer, Enrique Vidal, Eduard Zorita, Nil Üresin, Stefan F. Pinter, Guillaume J. Filion, Bernhard Payer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/d32434f601f34898a745cb1caef82c09
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