Changes of corneal tomography in patients with congenital blepharoptosis

Abstract The study aimed to evaluate the effect of drooped eyelid on corneal tomography in congenital blepharoptosis patients. Sixty-four patients with congenital blepharoptosis and 64 age- and sex- matched healthy subjects were included. According to the eyelid margin to corneal light reflex distan...

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Autores principales: Tiepei Zhu, Xin Ye, Peifang Xu, Jingyi Wang, Huina Zhang, Hailong Ni, Zhaoan Su, Juan Ye
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/d324ffc0df744505b85805d06e22eed3
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spelling oai:doaj.org-article:d324ffc0df744505b85805d06e22eed32021-12-02T15:05:58ZChanges of corneal tomography in patients with congenital blepharoptosis10.1038/s41598-017-06823-72045-2322https://doaj.org/article/d324ffc0df744505b85805d06e22eed32017-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-06823-7https://doaj.org/toc/2045-2322Abstract The study aimed to evaluate the effect of drooped eyelid on corneal tomography in congenital blepharoptosis patients. Sixty-four patients with congenital blepharoptosis and 64 age- and sex- matched healthy subjects were included. According to the eyelid margin to corneal light reflex distance (MRD), eyes with congenital blepharoptosis were categorized as mild, moderate, or severe. The eyes were scanned using the rotating Scheimpflug camera. Increased topometric parameters were observed in moderate and severe blepharoptosis. Back corneal elevations at the thinnest point were significant higher for mild (P = 0.009), moderate (P < 0.001), and severe (P < 0.001) congenital blepharoptosis compared with controls. Maximum Ambrósio’s relational thickness (ART) was decreased in eyes with severe blepharoptosis (P < 0.001). Fnal D values were significantly higher in moderate (P < 0.001) and severe blepharoptosis (P < 0.001) groups than that of controls. There were significant correlations between MRD and most corneal tomographic parameters. Our findings indicated there was a trend toward subclinical keratoconus-like changes in the corneas of congenital blepharoptosis, with the increase of ptosis severity.Tiepei ZhuXin YePeifang XuJingyi WangHuina ZhangHailong NiZhaoan SuJuan YeNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Tiepei Zhu
Xin Ye
Peifang Xu
Jingyi Wang
Huina Zhang
Hailong Ni
Zhaoan Su
Juan Ye
Changes of corneal tomography in patients with congenital blepharoptosis
description Abstract The study aimed to evaluate the effect of drooped eyelid on corneal tomography in congenital blepharoptosis patients. Sixty-four patients with congenital blepharoptosis and 64 age- and sex- matched healthy subjects were included. According to the eyelid margin to corneal light reflex distance (MRD), eyes with congenital blepharoptosis were categorized as mild, moderate, or severe. The eyes were scanned using the rotating Scheimpflug camera. Increased topometric parameters were observed in moderate and severe blepharoptosis. Back corneal elevations at the thinnest point were significant higher for mild (P = 0.009), moderate (P < 0.001), and severe (P < 0.001) congenital blepharoptosis compared with controls. Maximum Ambrósio’s relational thickness (ART) was decreased in eyes with severe blepharoptosis (P < 0.001). Fnal D values were significantly higher in moderate (P < 0.001) and severe blepharoptosis (P < 0.001) groups than that of controls. There were significant correlations between MRD and most corneal tomographic parameters. Our findings indicated there was a trend toward subclinical keratoconus-like changes in the corneas of congenital blepharoptosis, with the increase of ptosis severity.
format article
author Tiepei Zhu
Xin Ye
Peifang Xu
Jingyi Wang
Huina Zhang
Hailong Ni
Zhaoan Su
Juan Ye
author_facet Tiepei Zhu
Xin Ye
Peifang Xu
Jingyi Wang
Huina Zhang
Hailong Ni
Zhaoan Su
Juan Ye
author_sort Tiepei Zhu
title Changes of corneal tomography in patients with congenital blepharoptosis
title_short Changes of corneal tomography in patients with congenital blepharoptosis
title_full Changes of corneal tomography in patients with congenital blepharoptosis
title_fullStr Changes of corneal tomography in patients with congenital blepharoptosis
title_full_unstemmed Changes of corneal tomography in patients with congenital blepharoptosis
title_sort changes of corneal tomography in patients with congenital blepharoptosis
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/d324ffc0df744505b85805d06e22eed3
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