Surveying silicon nitride nanopores for glycomics and heparin quality assurance

The complexity of polysaccharides significantly complicates their analysis in comparison to other biopolymers. Here, the authors demonstrate that solid-state silicon nitride nanopore sensors can be used to reliably detect native polysaccharides and to perform a simple quality assurance assay on a po...

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Autores principales: Buddini Iroshika Karawdeniya, Y. M. Nuwan D. Y. Bandara, Jonathan W. Nichols, Robert B. Chevalier, Jason R. Dwyer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/d3271aaa488949b288cc8c483b914d73
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Sumario:The complexity of polysaccharides significantly complicates their analysis in comparison to other biopolymers. Here, the authors demonstrate that solid-state silicon nitride nanopore sensors can be used to reliably detect native polysaccharides and to perform a simple quality assurance assay on a polysaccharide therapeutic, heparin.