Surveying silicon nitride nanopores for glycomics and heparin quality assurance

The complexity of polysaccharides significantly complicates their analysis in comparison to other biopolymers. Here, the authors demonstrate that solid-state silicon nitride nanopore sensors can be used to reliably detect native polysaccharides and to perform a simple quality assurance assay on a po...

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Autores principales:	Buddini Iroshika Karawdeniya, Y. M. Nuwan D. Y. Bandara, Jonathan W. Nichols, Robert B. Chevalier, Jason R. Dwyer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d3271aaa488949b288cc8c483b914d73
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spelling	oai:doaj.org-article:d3271aaa488949b288cc8c483b914d732021-12-02T15:34:45ZSurveying silicon nitride nanopores for glycomics and heparin quality assurance10.1038/s41467-018-05751-y2041-1723https://doaj.org/article/d3271aaa488949b288cc8c483b914d732018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05751-yhttps://doaj.org/toc/2041-1723The complexity of polysaccharides significantly complicates their analysis in comparison to other biopolymers. Here, the authors demonstrate that solid-state silicon nitride nanopore sensors can be used to reliably detect native polysaccharides and to perform a simple quality assurance assay on a polysaccharide therapeutic, heparin.Buddini Iroshika KarawdeniyaY. M. Nuwan D. Y. BandaraJonathan W. NicholsRobert B. ChevalierJason R. DwyerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Buddini Iroshika Karawdeniya Y. M. Nuwan D. Y. Bandara Jonathan W. Nichols Robert B. Chevalier Jason R. Dwyer Surveying silicon nitride nanopores for glycomics and heparin quality assurance
description	The complexity of polysaccharides significantly complicates their analysis in comparison to other biopolymers. Here, the authors demonstrate that solid-state silicon nitride nanopore sensors can be used to reliably detect native polysaccharides and to perform a simple quality assurance assay on a polysaccharide therapeutic, heparin.
format	article
author	Buddini Iroshika Karawdeniya Y. M. Nuwan D. Y. Bandara Jonathan W. Nichols Robert B. Chevalier Jason R. Dwyer
author_facet	Buddini Iroshika Karawdeniya Y. M. Nuwan D. Y. Bandara Jonathan W. Nichols Robert B. Chevalier Jason R. Dwyer
author_sort	Buddini Iroshika Karawdeniya
title	Surveying silicon nitride nanopores for glycomics and heparin quality assurance
title_short	Surveying silicon nitride nanopores for glycomics and heparin quality assurance
title_full	Surveying silicon nitride nanopores for glycomics and heparin quality assurance
title_fullStr	Surveying silicon nitride nanopores for glycomics and heparin quality assurance
title_full_unstemmed	Surveying silicon nitride nanopores for glycomics and heparin quality assurance
title_sort	surveying silicon nitride nanopores for glycomics and heparin quality assurance
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/d3271aaa488949b288cc8c483b914d73
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Surveying silicon nitride nanopores for glycomics and heparin quality assurance

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