Antidiabetic Effects of Physical Activity: How It Helps to Control Type 2 Diabetes

Addisu Dabi Wake Nursing Department, College of Health Sciences, Arsi University, Assela, Oromia, EthiopiaCorrespondence: Addisu Dabi WakeNursing Department, College of Health Sciences, Arsi University, P.O. Box: 393/04, Asella, EthiopiaTel +251 910 2867 66Email addansa12@gmail.comAbstract: Despite...

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Autor principal:	Wake AD
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	diabetes mellitus exercise physical activity glycemic control type 2 dm Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/d3280c5b8d5c41cf81e788f0341fcac7
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spelling	oai:doaj.org-article:d3280c5b8d5c41cf81e788f0341fcac72021-12-02T09:43:02ZAntidiabetic Effects of Physical Activity: How It Helps to Control Type 2 Diabetes1178-7007https://doaj.org/article/d3280c5b8d5c41cf81e788f0341fcac72020-08-01T00:00:00Zhttps://www.dovepress.com/antidiabetic-effects-of-physical-activity-how-it-helps-to-control-type-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Addisu Dabi Wake Nursing Department, College of Health Sciences, Arsi University, Assela, Oromia, EthiopiaCorrespondence: Addisu Dabi WakeNursing Department, College of Health Sciences, Arsi University, P.O. Box: 393/04, Asella, EthiopiaTel +251 910 2867 66Email addansa12@gmail.comAbstract: Despite the improvements in clinical care of the patients, research updates, and public health interventions, there is still an increase in the prevalence, incidence, and mortality because of diabetes mellitus (DM). DM is a public health problem in both developed and developing countries. It has increased alarmingly, putting this disease in the dimension of an epidemic. Diabetes is associated with several complications which increase the risk of many serious health problems on the other side. Therefore, this review was aimed to discuss the antidiabetic effects of physical activity (PA) on type 2 DM (T2DM) by summarizing the significant studies on this topic. This review found that several studies have recommended the utilization of PA for the effective management of T2DM. PA is a non-pharmacologic therapy which is a significant strategy for the management of T2DM and is an appropriate lifestyle modification approach to be practiced by these patients. The studies showed that PA has antidiabetic effects which are evidenced by its substantial role in improving the blood glucose (BG) levels of the individuals with T2DM where it helps them to control their levels of glucose in the blood. It plays a significant role in glycemic control of this disease by lowering the BG levels through possible mechanisms such as decreasing insulin resistance, increasing production of glucose transporter type 4 (GLUT-4), lowering visceral adipose tissue (VAT), increasing pancreatic β-cell functions, using glucose for energy, and so on. In turn, the controlled glycemia helps to prevent the complications associated with uncontrolled T2DM and this would further improve the overall health of the patients and the burden on the health professionals as well. Finally, this review concludes that PA is the cornerstone in the management of T2DM. It also suggests that more attention is needed to its significance in the prevention, glycemic control, and its role in the management of the morbidity and mortality associated with T2DM. Practical PA recommendations and suggestions for the future direction of research in this area are also provided.Keywords: diabetes mellitus, physical activity, exercise, glycemic control, type 2 diabetesWake ADDove Medical Pressarticlediabetes mellitusexercisephysical activityglycemic controltype 2 dmSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 13, Pp 2909-2923 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	diabetes mellitus exercise physical activity glycemic control type 2 dm Specialties of internal medicine RC581-951
spellingShingle	diabetes mellitus exercise physical activity glycemic control type 2 dm Specialties of internal medicine RC581-951 Wake AD Antidiabetic Effects of Physical Activity: How It Helps to Control Type 2 Diabetes
description	Addisu Dabi Wake Nursing Department, College of Health Sciences, Arsi University, Assela, Oromia, EthiopiaCorrespondence: Addisu Dabi WakeNursing Department, College of Health Sciences, Arsi University, P.O. Box: 393/04, Asella, EthiopiaTel +251 910 2867 66Email addansa12@gmail.comAbstract: Despite the improvements in clinical care of the patients, research updates, and public health interventions, there is still an increase in the prevalence, incidence, and mortality because of diabetes mellitus (DM). DM is a public health problem in both developed and developing countries. It has increased alarmingly, putting this disease in the dimension of an epidemic. Diabetes is associated with several complications which increase the risk of many serious health problems on the other side. Therefore, this review was aimed to discuss the antidiabetic effects of physical activity (PA) on type 2 DM (T2DM) by summarizing the significant studies on this topic. This review found that several studies have recommended the utilization of PA for the effective management of T2DM. PA is a non-pharmacologic therapy which is a significant strategy for the management of T2DM and is an appropriate lifestyle modification approach to be practiced by these patients. The studies showed that PA has antidiabetic effects which are evidenced by its substantial role in improving the blood glucose (BG) levels of the individuals with T2DM where it helps them to control their levels of glucose in the blood. It plays a significant role in glycemic control of this disease by lowering the BG levels through possible mechanisms such as decreasing insulin resistance, increasing production of glucose transporter type 4 (GLUT-4), lowering visceral adipose tissue (VAT), increasing pancreatic β-cell functions, using glucose for energy, and so on. In turn, the controlled glycemia helps to prevent the complications associated with uncontrolled T2DM and this would further improve the overall health of the patients and the burden on the health professionals as well. Finally, this review concludes that PA is the cornerstone in the management of T2DM. It also suggests that more attention is needed to its significance in the prevention, glycemic control, and its role in the management of the morbidity and mortality associated with T2DM. Practical PA recommendations and suggestions for the future direction of research in this area are also provided.Keywords: diabetes mellitus, physical activity, exercise, glycemic control, type 2 diabetes
format	article
author	Wake AD
author_facet	Wake AD
author_sort	Wake AD
title	Antidiabetic Effects of Physical Activity: How It Helps to Control Type 2 Diabetes
title_short	Antidiabetic Effects of Physical Activity: How It Helps to Control Type 2 Diabetes
title_full	Antidiabetic Effects of Physical Activity: How It Helps to Control Type 2 Diabetes
title_fullStr	Antidiabetic Effects of Physical Activity: How It Helps to Control Type 2 Diabetes
title_full_unstemmed	Antidiabetic Effects of Physical Activity: How It Helps to Control Type 2 Diabetes
title_sort	antidiabetic effects of physical activity: how it helps to control type 2 diabetes
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/d3280c5b8d5c41cf81e788f0341fcac7
work_keys_str_mv	AT wakead antidiabeticeffectsofphysicalactivityhowithelpstocontroltype2diabetes
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Antidiabetic Effects of Physical Activity: How It Helps to Control Type 2 Diabetes

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