Ecological plasticity to ions concentration determines genetic response and dominance of Anopheles coluzzii larvae in urban coastal habitats of Central Africa

Abstract In Central Africa, the malaria vector Anopheles coluzzii is predominant in urban and coastal habitats. However, little is known about the environmental factors that may be involved in this process. Here, we performed an analysis of 28 physicochemical characteristics of 59 breeding sites acr...

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Autores principales:	Neil M. Longo-Pendy, Billy Tene-Fossog, Robert E. Tawedi, Ousman Akone-Ella, Celine Toty, Nil Rahola, Jean-Jacques Braun, Nicolas Berthet, Pierre Kengne, Carlo Costantini, Diego Ayala
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/d32a4c47de9f4fee9b179d4696cd33c4
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spelling	oai:doaj.org-article:d32a4c47de9f4fee9b179d4696cd33c42021-12-02T14:53:49ZEcological plasticity to ions concentration determines genetic response and dominance of Anopheles coluzzii larvae in urban coastal habitats of Central Africa10.1038/s41598-021-94258-62045-2322https://doaj.org/article/d32a4c47de9f4fee9b179d4696cd33c42021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-94258-6https://doaj.org/toc/2045-2322Abstract In Central Africa, the malaria vector Anopheles coluzzii is predominant in urban and coastal habitats. However, little is known about the environmental factors that may be involved in this process. Here, we performed an analysis of 28 physicochemical characteristics of 59 breeding sites across 5 urban and rural sites in coastal areas of Central Africa. We then modelled the relative frequency of An. coluzzii larvae to these physicochemical parameters in order to investigate environmental patterns. Then, we assessed the expression variation of 10 candidate genes in An. coluzzii, previously incriminated with insecticide resistance and osmoregulation in urban settings. Our results confirmed the ecological plasticity of An. coluzzii larvae to breed in a large range of aquatic conditions and its predominance in breeding sites rich in ions. Gene expression patterns were comparable between urban and rural habitats, suggesting a broad response to ions concentrations of whatever origin. Altogether, An. coluzzii exhibits a plastic response to occupy both coastal and urban habitats. This entails important consequences for malaria control in the context of the rapid urban expansion in Africa in the coming years.Neil M. Longo-PendyBilly Tene-FossogRobert E. TawediOusman Akone-EllaCeline TotyNil RaholaJean-Jacques BraunNicolas BerthetPierre KengneCarlo CostantiniDiego AyalaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Neil M. Longo-Pendy Billy Tene-Fossog Robert E. Tawedi Ousman Akone-Ella Celine Toty Nil Rahola Jean-Jacques Braun Nicolas Berthet Pierre Kengne Carlo Costantini Diego Ayala Ecological plasticity to ions concentration determines genetic response and dominance of Anopheles coluzzii larvae in urban coastal habitats of Central Africa
description	Abstract In Central Africa, the malaria vector Anopheles coluzzii is predominant in urban and coastal habitats. However, little is known about the environmental factors that may be involved in this process. Here, we performed an analysis of 28 physicochemical characteristics of 59 breeding sites across 5 urban and rural sites in coastal areas of Central Africa. We then modelled the relative frequency of An. coluzzii larvae to these physicochemical parameters in order to investigate environmental patterns. Then, we assessed the expression variation of 10 candidate genes in An. coluzzii, previously incriminated with insecticide resistance and osmoregulation in urban settings. Our results confirmed the ecological plasticity of An. coluzzii larvae to breed in a large range of aquatic conditions and its predominance in breeding sites rich in ions. Gene expression patterns were comparable between urban and rural habitats, suggesting a broad response to ions concentrations of whatever origin. Altogether, An. coluzzii exhibits a plastic response to occupy both coastal and urban habitats. This entails important consequences for malaria control in the context of the rapid urban expansion in Africa in the coming years.
format	article
author	Neil M. Longo-Pendy Billy Tene-Fossog Robert E. Tawedi Ousman Akone-Ella Celine Toty Nil Rahola Jean-Jacques Braun Nicolas Berthet Pierre Kengne Carlo Costantini Diego Ayala
author_facet	Neil M. Longo-Pendy Billy Tene-Fossog Robert E. Tawedi Ousman Akone-Ella Celine Toty Nil Rahola Jean-Jacques Braun Nicolas Berthet Pierre Kengne Carlo Costantini Diego Ayala
author_sort	Neil M. Longo-Pendy
title	Ecological plasticity to ions concentration determines genetic response and dominance of Anopheles coluzzii larvae in urban coastal habitats of Central Africa
title_short	Ecological plasticity to ions concentration determines genetic response and dominance of Anopheles coluzzii larvae in urban coastal habitats of Central Africa
title_full	Ecological plasticity to ions concentration determines genetic response and dominance of Anopheles coluzzii larvae in urban coastal habitats of Central Africa
title_fullStr	Ecological plasticity to ions concentration determines genetic response and dominance of Anopheles coluzzii larvae in urban coastal habitats of Central Africa
title_full_unstemmed	Ecological plasticity to ions concentration determines genetic response and dominance of Anopheles coluzzii larvae in urban coastal habitats of Central Africa
title_sort	ecological plasticity to ions concentration determines genetic response and dominance of anopheles coluzzii larvae in urban coastal habitats of central africa
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d32a4c47de9f4fee9b179d4696cd33c4
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Ecological plasticity to ions concentration determines genetic response and dominance of Anopheles coluzzii larvae in urban coastal habitats of Central Africa

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