Immune evasion of Borrelia miyamotoi: CbiA, a novel outer surface protein exhibiting complement binding and inactivating properties
Abstract Borrelia (B.) miyamotoi, an emerging tick-borne relapsing fever spirochete, resists complement-mediated killing. To decipher the molecular principles of immune evasion, we sought to identify determinants contributing to complement resistance. Employing bioinformatics, we identified a gene e...
Guardado en:
Autores principales: | Florian Röttgerding, Alex Wagemakers, Joris Koetsveld, Volker Fingerle, Michael Kirschfink, Joppe W. Hovius, Peter F. Zipfel, Reinhard Wallich, Peter Kraiczy |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/d332e145360d4ee0b985697b6a40fcbf |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Interaction between Borrelia miyamotoi variable major proteins Vlp15/16 and Vlp18 with plasminogen and complement
por: Frederik L. Schmidt, et al.
Publicado: (2021) -
Isolation of Borrelia miyamotoi and other Borreliae using a modified BSK medium
por: Adam J. Replogle, et al.
Publicado: (2021) -
Borrelia valaisiana resist complement-mediated killing independently of the recruitment of immune regulators and inactivation of complement components.
por: Jasmin Schwab, et al.
Publicado: (2013) -
Borrelia miyamotoi in Human-Biting Ticks, United States, 2013–2019
por: Guang Xu, et al.
Publicado: (2021) -
Vitronectin binding protein, BOM1093, confers serum resistance on Borrelia miyamotoi
por: Kozue Sato, et al.
Publicado: (2021)