Structural and mechanistic characterization of an archaeal-like chaperonin from a thermophilic bacterium

Chaperonins (CPNs) are ATP-dependent protein-folding machines. Here the authors present the open and closed crystal structures of a Group III CPN from the thermophilic bacterium Carboxydothermus hydrogenoformans, discuss its mechanism and structurally compare it with Group I and II CPNs.

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Autores principales: Young Jun An, Sara E. Rowland, Jung-Hyun Na, Dario Spigolon, Seung Kon Hong, Yeo Joon Yoon, Jung-Hyun Lee, Frank T. Robb, Sun-Shin Cha
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/d3341cf5c0da4ac9833bdafce3c7b169
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spelling oai:doaj.org-article:d3341cf5c0da4ac9833bdafce3c7b1692021-12-02T17:06:03ZStructural and mechanistic characterization of an archaeal-like chaperonin from a thermophilic bacterium10.1038/s41467-017-00980-z2041-1723https://doaj.org/article/d3341cf5c0da4ac9833bdafce3c7b1692017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00980-zhttps://doaj.org/toc/2041-1723Chaperonins (CPNs) are ATP-dependent protein-folding machines. Here the authors present the open and closed crystal structures of a Group III CPN from the thermophilic bacterium Carboxydothermus hydrogenoformans, discuss its mechanism and structurally compare it with Group I and II CPNs.Young Jun AnSara E. RowlandJung-Hyun NaDario SpigolonSeung Kon HongYeo Joon YoonJung-Hyun LeeFrank T. RobbSun-Shin ChaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Young Jun An
Sara E. Rowland
Jung-Hyun Na
Dario Spigolon
Seung Kon Hong
Yeo Joon Yoon
Jung-Hyun Lee
Frank T. Robb
Sun-Shin Cha
Structural and mechanistic characterization of an archaeal-like chaperonin from a thermophilic bacterium
description Chaperonins (CPNs) are ATP-dependent protein-folding machines. Here the authors present the open and closed crystal structures of a Group III CPN from the thermophilic bacterium Carboxydothermus hydrogenoformans, discuss its mechanism and structurally compare it with Group I and II CPNs.
format article
author Young Jun An
Sara E. Rowland
Jung-Hyun Na
Dario Spigolon
Seung Kon Hong
Yeo Joon Yoon
Jung-Hyun Lee
Frank T. Robb
Sun-Shin Cha
author_facet Young Jun An
Sara E. Rowland
Jung-Hyun Na
Dario Spigolon
Seung Kon Hong
Yeo Joon Yoon
Jung-Hyun Lee
Frank T. Robb
Sun-Shin Cha
author_sort Young Jun An
title Structural and mechanistic characterization of an archaeal-like chaperonin from a thermophilic bacterium
title_short Structural and mechanistic characterization of an archaeal-like chaperonin from a thermophilic bacterium
title_full Structural and mechanistic characterization of an archaeal-like chaperonin from a thermophilic bacterium
title_fullStr Structural and mechanistic characterization of an archaeal-like chaperonin from a thermophilic bacterium
title_full_unstemmed Structural and mechanistic characterization of an archaeal-like chaperonin from a thermophilic bacterium
title_sort structural and mechanistic characterization of an archaeal-like chaperonin from a thermophilic bacterium
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/d3341cf5c0da4ac9833bdafce3c7b169
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