Structural and mechanistic characterization of an archaeal-like chaperonin from a thermophilic bacterium
Chaperonins (CPNs) are ATP-dependent protein-folding machines. Here the authors present the open and closed crystal structures of a Group III CPN from the thermophilic bacterium Carboxydothermus hydrogenoformans, discuss its mechanism and structurally compare it with Group I and II CPNs.
Guardado en:
Autores principales: | , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/d3341cf5c0da4ac9833bdafce3c7b169 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:d3341cf5c0da4ac9833bdafce3c7b169 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:d3341cf5c0da4ac9833bdafce3c7b1692021-12-02T17:06:03ZStructural and mechanistic characterization of an archaeal-like chaperonin from a thermophilic bacterium10.1038/s41467-017-00980-z2041-1723https://doaj.org/article/d3341cf5c0da4ac9833bdafce3c7b1692017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00980-zhttps://doaj.org/toc/2041-1723Chaperonins (CPNs) are ATP-dependent protein-folding machines. Here the authors present the open and closed crystal structures of a Group III CPN from the thermophilic bacterium Carboxydothermus hydrogenoformans, discuss its mechanism and structurally compare it with Group I and II CPNs.Young Jun AnSara E. RowlandJung-Hyun NaDario SpigolonSeung Kon HongYeo Joon YoonJung-Hyun LeeFrank T. RobbSun-Shin ChaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Young Jun An Sara E. Rowland Jung-Hyun Na Dario Spigolon Seung Kon Hong Yeo Joon Yoon Jung-Hyun Lee Frank T. Robb Sun-Shin Cha Structural and mechanistic characterization of an archaeal-like chaperonin from a thermophilic bacterium |
description |
Chaperonins (CPNs) are ATP-dependent protein-folding machines. Here the authors present the open and closed crystal structures of a Group III CPN from the thermophilic bacterium Carboxydothermus hydrogenoformans, discuss its mechanism and structurally compare it with Group I and II CPNs. |
format |
article |
author |
Young Jun An Sara E. Rowland Jung-Hyun Na Dario Spigolon Seung Kon Hong Yeo Joon Yoon Jung-Hyun Lee Frank T. Robb Sun-Shin Cha |
author_facet |
Young Jun An Sara E. Rowland Jung-Hyun Na Dario Spigolon Seung Kon Hong Yeo Joon Yoon Jung-Hyun Lee Frank T. Robb Sun-Shin Cha |
author_sort |
Young Jun An |
title |
Structural and mechanistic characterization of an archaeal-like chaperonin from a thermophilic bacterium |
title_short |
Structural and mechanistic characterization of an archaeal-like chaperonin from a thermophilic bacterium |
title_full |
Structural and mechanistic characterization of an archaeal-like chaperonin from a thermophilic bacterium |
title_fullStr |
Structural and mechanistic characterization of an archaeal-like chaperonin from a thermophilic bacterium |
title_full_unstemmed |
Structural and mechanistic characterization of an archaeal-like chaperonin from a thermophilic bacterium |
title_sort |
structural and mechanistic characterization of an archaeal-like chaperonin from a thermophilic bacterium |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/d3341cf5c0da4ac9833bdafce3c7b169 |
work_keys_str_mv |
AT youngjunan structuralandmechanisticcharacterizationofanarchaeallikechaperoninfromathermophilicbacterium AT saraerowland structuralandmechanisticcharacterizationofanarchaeallikechaperoninfromathermophilicbacterium AT junghyunna structuralandmechanisticcharacterizationofanarchaeallikechaperoninfromathermophilicbacterium AT dariospigolon structuralandmechanisticcharacterizationofanarchaeallikechaperoninfromathermophilicbacterium AT seungkonhong structuralandmechanisticcharacterizationofanarchaeallikechaperoninfromathermophilicbacterium AT yeojoonyoon structuralandmechanisticcharacterizationofanarchaeallikechaperoninfromathermophilicbacterium AT junghyunlee structuralandmechanisticcharacterizationofanarchaeallikechaperoninfromathermophilicbacterium AT franktrobb structuralandmechanisticcharacterizationofanarchaeallikechaperoninfromathermophilicbacterium AT sunshincha structuralandmechanisticcharacterizationofanarchaeallikechaperoninfromathermophilicbacterium |
_version_ |
1718381759175852032 |