Monocyte dysfunction in decompensated cirrhosis is mediated by the prostaglandin E2-EP4 pathway
Background & Aims: Infection is a major problem in advanced liver disease secondary to monocyte dysfunction. Elevated prostaglandin (PG)E2 is a mediator of monocyte dysfunction in cirrhosis; thus, we examined PGE2 signalling in outpatients with ascites and in patients hospitalised with acute...
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Autores principales: | Alexander A. Maini, Natalia Becares, Louise China, Thais H. Tittanegro, Amit Patel, Roel P.H. De Maeyer, Nekisa Zakeri, Tu Vinh Long, Lucy Ly, Derek W. Gilroy, Alastair O’Brien |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/d3345bc59a7b459581475c760ed2675d |
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