Inhibition of NHEJ repair by type II-A CRISPR-Cas systems in bacteria

The double-strand breaks generated by CRISPR-Cas systems are the target of multiple DNA repair pathways. Here the authors find incompatibility between NHEJ and type II-A CRISPR-Cas systems due to Csn2 mediated inhibition of end-joining.

Guardado en:

Detalles Bibliográficos
Autores principales:	Aude Bernheim, Alicia Calvo-Villamañán, Clovis Basier, Lun Cui, Eduardo P. C. Rocha, Marie Touchon, David Bikard
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d335f034b2614a128c2753ae094ff372
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:d335f034b2614a128c2753ae094ff372
record_format	dspace
spelling	oai:doaj.org-article:d335f034b2614a128c2753ae094ff3722021-12-02T15:38:56ZInhibition of NHEJ repair by type II-A CRISPR-Cas systems in bacteria10.1038/s41467-017-02350-12041-1723https://doaj.org/article/d335f034b2614a128c2753ae094ff3722017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02350-1https://doaj.org/toc/2041-1723The double-strand breaks generated by CRISPR-Cas systems are the target of multiple DNA repair pathways. Here the authors find incompatibility between NHEJ and type II-A CRISPR-Cas systems due to Csn2 mediated inhibition of end-joining.Aude BernheimAlicia Calvo-VillamañánClovis BasierLun CuiEduardo P. C. RochaMarie TouchonDavid BikardNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Aude Bernheim Alicia Calvo-Villamañán Clovis Basier Lun Cui Eduardo P. C. Rocha Marie Touchon David Bikard Inhibition of NHEJ repair by type II-A CRISPR-Cas systems in bacteria
description	The double-strand breaks generated by CRISPR-Cas systems are the target of multiple DNA repair pathways. Here the authors find incompatibility between NHEJ and type II-A CRISPR-Cas systems due to Csn2 mediated inhibition of end-joining.
format	article
author	Aude Bernheim Alicia Calvo-Villamañán Clovis Basier Lun Cui Eduardo P. C. Rocha Marie Touchon David Bikard
author_facet	Aude Bernheim Alicia Calvo-Villamañán Clovis Basier Lun Cui Eduardo P. C. Rocha Marie Touchon David Bikard
author_sort	Aude Bernheim
title	Inhibition of NHEJ repair by type II-A CRISPR-Cas systems in bacteria
title_short	Inhibition of NHEJ repair by type II-A CRISPR-Cas systems in bacteria
title_full	Inhibition of NHEJ repair by type II-A CRISPR-Cas systems in bacteria
title_fullStr	Inhibition of NHEJ repair by type II-A CRISPR-Cas systems in bacteria
title_full_unstemmed	Inhibition of NHEJ repair by type II-A CRISPR-Cas systems in bacteria
title_sort	inhibition of nhej repair by type ii-a crispr-cas systems in bacteria
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/d335f034b2614a128c2753ae094ff372
work_keys_str_mv	AT audebernheim inhibitionofnhejrepairbytypeiiacrisprcassystemsinbacteria AT aliciacalvovillamanan inhibitionofnhejrepairbytypeiiacrisprcassystemsinbacteria AT clovisbasier inhibitionofnhejrepairbytypeiiacrisprcassystemsinbacteria AT luncui inhibitionofnhejrepairbytypeiiacrisprcassystemsinbacteria AT eduardopcrocha inhibitionofnhejrepairbytypeiiacrisprcassystemsinbacteria AT marietouchon inhibitionofnhejrepairbytypeiiacrisprcassystemsinbacteria AT davidbikard inhibitionofnhejrepairbytypeiiacrisprcassystemsinbacteria
_version_	1718386076533391360

Inhibition of NHEJ repair by type II-A CRISPR-Cas systems in bacteria

Ejemplares similares