IL-15 promotes human myogenesis and mitigates the detrimental effects of TNFα on myotube development

Abstract Studies in murine cell lines and in mouse models suggest that IL-15 promotes myogenesis and may protect against the inflammation-mediated skeletal muscle atrophy which occurs in sarcopenia and cachexia. The effects of IL-15 on human skeletal muscle growth and development remain largely unch...

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Auteurs principaux: Mary F. O’Leary, Graham R. Wallace, Andrew J. Bennett, Kostas Tsintzas, Simon W. Jones
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/d33a33ba397f4c0e9a035dc7e4ebe3f0
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