Using answer set programming to integrate RNA expression with signalling pathway information to infer how mutations affect ageing.

A challenge of systems biology is to integrate incomplete knowledge on pathways with existing experimental data sets and relate these to measured phenotypes. Research on ageing often generates such incomplete data, creating difficulties in integrating RNA expression with information about biological...

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Autores principales: Irene Papatheodorou, Matthias Ziehm, Daniela Wieser, Nazif Alic, Linda Partridge, Janet M Thornton
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/d33dc7059f154716bc11f6c07d81d475
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