The Arf GTPase-Activating Protein Family Is Exploited by <named-content content-type="genus-species">Salmonella enterica</named-content> Serovar Typhimurium To Invade Nonphagocytic Host Cells

ABSTRACT To establish intracellular infections, Salmonella bacteria trigger host cell membrane ruffling and invasion by subverting cellular Arf guanine nucleotide exchange factors (GEFs) that activate Arf1 and Arf6 GTPases by promoting GTP binding. A family of cellular Arf GTPase-activating proteins...

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Bibliographic Details
Main Authors: Anthony C. Davidson, Daniel Humphreys, Andrew B. E. Brooks, Peter J. Hume, Vassilis Koronakis
Format: article
Language:EN
Published: American Society for Microbiology 2015
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Online Access:https://doaj.org/article/d3438ea1bd3d4b8da844642b3c3ac5ac
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