Functional genomic analysis identifies miRNA repertoire regulating C. elegans oocyte development

Biogenesis and function of miRNAs in somatic cells is well characterized, but their role in the germline has not been established. Here the authors identify and characterize Drosha independent and dependent miRNAs during C. elegans oogenesis, revealing their roles in meiotic progression and oocyte d...

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Autores principales:	Amanda L. Minogue, Michael R. Tackett, Elnaz Atabakhsh, Genesis Tejada, Swathi Arur
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d34af9cea2764ebaa8f0e7196aa96005
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spelling	oai:doaj.org-article:d34af9cea2764ebaa8f0e7196aa960052021-12-02T17:31:27ZFunctional genomic analysis identifies miRNA repertoire regulating C. elegans oocyte development10.1038/s41467-018-07791-w2041-1723https://doaj.org/article/d34af9cea2764ebaa8f0e7196aa960052018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07791-whttps://doaj.org/toc/2041-1723Biogenesis and function of miRNAs in somatic cells is well characterized, but their role in the germline has not been established. Here the authors identify and characterize Drosha independent and dependent miRNAs during C. elegans oogenesis, revealing their roles in meiotic progression and oocyte development.Amanda L. MinogueMichael R. TackettElnaz AtabakhshGenesis TejadaSwathi ArurNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Amanda L. Minogue Michael R. Tackett Elnaz Atabakhsh Genesis Tejada Swathi Arur Functional genomic analysis identifies miRNA repertoire regulating C. elegans oocyte development
description	Biogenesis and function of miRNAs in somatic cells is well characterized, but their role in the germline has not been established. Here the authors identify and characterize Drosha independent and dependent miRNAs during C. elegans oogenesis, revealing their roles in meiotic progression and oocyte development.
format	article
author	Amanda L. Minogue Michael R. Tackett Elnaz Atabakhsh Genesis Tejada Swathi Arur
author_facet	Amanda L. Minogue Michael R. Tackett Elnaz Atabakhsh Genesis Tejada Swathi Arur
author_sort	Amanda L. Minogue
title	Functional genomic analysis identifies miRNA repertoire regulating C. elegans oocyte development
title_short	Functional genomic analysis identifies miRNA repertoire regulating C. elegans oocyte development
title_full	Functional genomic analysis identifies miRNA repertoire regulating C. elegans oocyte development
title_fullStr	Functional genomic analysis identifies miRNA repertoire regulating C. elegans oocyte development
title_full_unstemmed	Functional genomic analysis identifies miRNA repertoire regulating C. elegans oocyte development
title_sort	functional genomic analysis identifies mirna repertoire regulating c. elegans oocyte development
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/d34af9cea2764ebaa8f0e7196aa96005
work_keys_str_mv	AT amandalminogue functionalgenomicanalysisidentifiesmirnarepertoireregulatingcelegansoocytedevelopment AT michaelrtackett functionalgenomicanalysisidentifiesmirnarepertoireregulatingcelegansoocytedevelopment AT elnazatabakhsh functionalgenomicanalysisidentifiesmirnarepertoireregulatingcelegansoocytedevelopment AT genesistejada functionalgenomicanalysisidentifiesmirnarepertoireregulatingcelegansoocytedevelopment AT swathiarur functionalgenomicanalysisidentifiesmirnarepertoireregulatingcelegansoocytedevelopment
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Functional genomic analysis identifies miRNA repertoire regulating C. elegans oocyte development

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