Ultra-bright Raman dots for multiplexed optical imaging

Raman-based imaging of biomarkers is often challenging due to low sensitivity. Here, the authors use a swelling-diffusion approach to develop a series of Raman probes that are both ultra-bright and compact in size, and demonstrate multiplexed imaging of specific protein targets in cells and tissue s...

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Autores principales:	Zhilun Zhao, Chen Chen, Shixuan Wei, Hanqing Xiong, Fanghao Hu, Yupeng Miao, Tianwei Jin, Wei Min
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d34bce3702eb483081e6f24229cdc0d8
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spelling	oai:doaj.org-article:d34bce3702eb483081e6f24229cdc0d82021-12-02T13:33:04ZUltra-bright Raman dots for multiplexed optical imaging10.1038/s41467-021-21570-02041-1723https://doaj.org/article/d34bce3702eb483081e6f24229cdc0d82021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21570-0https://doaj.org/toc/2041-1723Raman-based imaging of biomarkers is often challenging due to low sensitivity. Here, the authors use a swelling-diffusion approach to develop a series of Raman probes that are both ultra-bright and compact in size, and demonstrate multiplexed imaging of specific protein targets in cells and tissue slices.Zhilun ZhaoChen ChenShixuan WeiHanqing XiongFanghao HuYupeng MiaoTianwei JinWei MinNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhilun Zhao Chen Chen Shixuan Wei Hanqing Xiong Fanghao Hu Yupeng Miao Tianwei Jin Wei Min Ultra-bright Raman dots for multiplexed optical imaging
description	Raman-based imaging of biomarkers is often challenging due to low sensitivity. Here, the authors use a swelling-diffusion approach to develop a series of Raman probes that are both ultra-bright and compact in size, and demonstrate multiplexed imaging of specific protein targets in cells and tissue slices.
format	article
author	Zhilun Zhao Chen Chen Shixuan Wei Hanqing Xiong Fanghao Hu Yupeng Miao Tianwei Jin Wei Min
author_facet	Zhilun Zhao Chen Chen Shixuan Wei Hanqing Xiong Fanghao Hu Yupeng Miao Tianwei Jin Wei Min
author_sort	Zhilun Zhao
title	Ultra-bright Raman dots for multiplexed optical imaging
title_short	Ultra-bright Raman dots for multiplexed optical imaging
title_full	Ultra-bright Raman dots for multiplexed optical imaging
title_fullStr	Ultra-bright Raman dots for multiplexed optical imaging
title_full_unstemmed	Ultra-bright Raman dots for multiplexed optical imaging
title_sort	ultra-bright raman dots for multiplexed optical imaging
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d34bce3702eb483081e6f24229cdc0d8
work_keys_str_mv	AT zhilunzhao ultrabrightramandotsformultiplexedopticalimaging AT chenchen ultrabrightramandotsformultiplexedopticalimaging AT shixuanwei ultrabrightramandotsformultiplexedopticalimaging AT hanqingxiong ultrabrightramandotsformultiplexedopticalimaging AT fanghaohu ultrabrightramandotsformultiplexedopticalimaging AT yupengmiao ultrabrightramandotsformultiplexedopticalimaging AT tianweijin ultrabrightramandotsformultiplexedopticalimaging AT weimin ultrabrightramandotsformultiplexedopticalimaging
_version_	1718392884873396224

Ultra-bright Raman dots for multiplexed optical imaging

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