Chemotherapy induces dynamic immune responses in breast cancers that impact treatment outcome

Chemotherapy induces dynamic immune responses in breast cancers that impact treatment outcome

Neoadjuvant chemotherapy is a therapeutic option for the treatment of breast cancer. Here, the authors characterize changes in the gene expression profiles and immune microenvironment in serial breast cancer biopsies taken before, during and after neoadjuvant chemotherapy.

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Autores principales: Yeon Hee Park, Samir Lal, Jeong Eon Lee, Yoon-La Choi, Ji Wen, Sripad Ram, Ying Ding, Soo-Hyeon Lee, Eric Powell, Se Kyung Lee, Jong Han Yu, Keith A. Ching, Jae-Yong Nam, Seok Won Kim, Seok Jin Nam, Ji-Yeon Kim, Soo Youn Cho, Seri Park, Jinho Kim, Soohyn Hwang, Yu Jin Kim, Vinicius Bonato, Diane Fernandez, Shibing Deng, Shuoguo Wang, Hyuntae Shin, Eun-Suk Kang, Woong-Yang Park, Paul A. Rejto, Jadwiga Bienkowska, Zhengyan Kan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/d34ef5fb3216481893b451cd685dff30
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spelling oai:doaj.org-article:d34ef5fb3216481893b451cd685dff302021-12-02T14:41:02ZChemotherapy induces dynamic immune responses in breast cancers that impact treatment outcome10.1038/s41467-020-19933-02041-1723https://doaj.org/article/d34ef5fb3216481893b451cd685dff302020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19933-0https://doaj.org/toc/2041-1723Neoadjuvant chemotherapy is a therapeutic option for the treatment of breast cancer. Here, the authors characterize changes in the gene expression profiles and immune microenvironment in serial breast cancer biopsies taken before, during and after neoadjuvant chemotherapy.Yeon Hee ParkSamir LalJeong Eon LeeYoon-La ChoiJi WenSripad RamYing DingSoo-Hyeon LeeEric PowellSe Kyung LeeJong Han YuKeith A. ChingJae-Yong NamSeok Won KimSeok Jin NamJi-Yeon KimSoo Youn ChoSeri ParkJinho KimSoohyn HwangYu Jin KimVinicius BonatoDiane FernandezShibing DengShuoguo WangHyuntae ShinEun-Suk KangWoong-Yang ParkPaul A. RejtoJadwiga BienkowskaZhengyan KanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yeon Hee Park
Samir Lal
Jeong Eon Lee
Yoon-La Choi
Ji Wen
Sripad Ram
Ying Ding
Soo-Hyeon Lee
Eric Powell
Se Kyung Lee
Jong Han Yu
Keith A. Ching
Jae-Yong Nam
Seok Won Kim
Seok Jin Nam
Ji-Yeon Kim
Soo Youn Cho
Seri Park
Jinho Kim
Soohyn Hwang
Yu Jin Kim
Vinicius Bonato
Diane Fernandez
Shibing Deng
Shuoguo Wang
Hyuntae Shin
Eun-Suk Kang
Woong-Yang Park
Paul A. Rejto
Jadwiga Bienkowska
Zhengyan Kan
Chemotherapy induces dynamic immune responses in breast cancers that impact treatment outcome
description Neoadjuvant chemotherapy is a therapeutic option for the treatment of breast cancer. Here, the authors characterize changes in the gene expression profiles and immune microenvironment in serial breast cancer biopsies taken before, during and after neoadjuvant chemotherapy.
format article
author Yeon Hee Park
Samir Lal
Jeong Eon Lee
Yoon-La Choi
Ji Wen
Sripad Ram
Ying Ding
Soo-Hyeon Lee
Eric Powell
Se Kyung Lee
Jong Han Yu
Keith A. Ching
Jae-Yong Nam
Seok Won Kim
Seok Jin Nam
Ji-Yeon Kim
Soo Youn Cho
Seri Park
Jinho Kim
Soohyn Hwang
Yu Jin Kim
Vinicius Bonato
Diane Fernandez
Shibing Deng
Shuoguo Wang
Hyuntae Shin
Eun-Suk Kang
Woong-Yang Park
Paul A. Rejto
Jadwiga Bienkowska
Zhengyan Kan
author_facet Yeon Hee Park
Samir Lal
Jeong Eon Lee
Yoon-La Choi
Ji Wen
Sripad Ram
Ying Ding
Soo-Hyeon Lee
Eric Powell
Se Kyung Lee
Jong Han Yu
Keith A. Ching
Jae-Yong Nam
Seok Won Kim
Seok Jin Nam
Ji-Yeon Kim
Soo Youn Cho
Seri Park
Jinho Kim
Soohyn Hwang
Yu Jin Kim
Vinicius Bonato
Diane Fernandez
Shibing Deng
Shuoguo Wang
Hyuntae Shin
Eun-Suk Kang
Woong-Yang Park
Paul A. Rejto
Jadwiga Bienkowska
Zhengyan Kan
author_sort Yeon Hee Park
title Chemotherapy induces dynamic immune responses in breast cancers that impact treatment outcome
title_short Chemotherapy induces dynamic immune responses in breast cancers that impact treatment outcome
title_full Chemotherapy induces dynamic immune responses in breast cancers that impact treatment outcome
title_fullStr Chemotherapy induces dynamic immune responses in breast cancers that impact treatment outcome
title_full_unstemmed Chemotherapy induces dynamic immune responses in breast cancers that impact treatment outcome
title_sort chemotherapy induces dynamic immune responses in breast cancers that impact treatment outcome
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/d34ef5fb3216481893b451cd685dff30
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