The association between water hardness and xerosis-Results from the Danish Blood Donor Study.
<h4>Background</h4>The pathophysiology of xerosis depends on extrinsic and intrinsic exposures. Residential hard water may constitute such an exposure.<h4>Objectives</h4>To estimate the prevalence of xerosis and to compare water hardness exposure in blood donors with and with...
Guardado en:
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/d35114992e0549a48dcbb9ba4b8a6ba0 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:d35114992e0549a48dcbb9ba4b8a6ba0 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:d35114992e0549a48dcbb9ba4b8a6ba02021-12-02T20:11:07ZThe association between water hardness and xerosis-Results from the Danish Blood Donor Study.1932-620310.1371/journal.pone.0252462https://doaj.org/article/d35114992e0549a48dcbb9ba4b8a6ba02021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0252462https://doaj.org/toc/1932-6203<h4>Background</h4>The pathophysiology of xerosis depends on extrinsic and intrinsic exposures. Residential hard water may constitute such an exposure.<h4>Objectives</h4>To estimate the prevalence of xerosis and to compare water hardness exposure in blood donors with and without xerosis.<h4>Methods</h4>In this retrospective cohort study in 2018-2019, blood donors with self-reported moderately or severely dry skin were compared to blood donors without dry skin. Blood donors with ichthyosis, lichen planus and psoriasis were excluded. Water hardness data was collected from the Geology Survey of Denmark and Greenland.<h4>Results</h4>Overall, 4,748 of 30,721 (15.5%; 95% confidence interval 15.1-15.9%) blood donors had xerosis. After excluding blood donors with ichthyosis, lichen planus and psoriasis, 4,416 blood donors (2,559 females; median age 38.4 years [interquartile range 28.0-49.8]; 700 smokers) remained in this study. Water softer than 12-24 degrees Deutsche härte was associated with decreased probability of xerosis (odds ratio 0.83; 95% confidence interval 0.74-0.94) and water harder than 12-24 degrees Deutsche härte was associated with increased probability of xerosis (odds ratio 1.22; 95% confidence interval 1.03-1.45). The association between water hardness and xerosis remained significant after excluding blood donors with dermatitis.<h4>Conclusions</h4>Water hardness is associated with xerosis independent of other dermatoses.Mattias A S HenningKristina S IblerHenrik UllumChristian ErikstrupMie T BruunKristoffer S BurgdorfKhoa M DinhAndreas RigasLise W ThørnerOle B PedersenGregor B JemecPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 6, p e0252462 (2021) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Medicine R Science Q |
spellingShingle |
Medicine R Science Q Mattias A S Henning Kristina S Ibler Henrik Ullum Christian Erikstrup Mie T Bruun Kristoffer S Burgdorf Khoa M Dinh Andreas Rigas Lise W Thørner Ole B Pedersen Gregor B Jemec The association between water hardness and xerosis-Results from the Danish Blood Donor Study. |
description |
<h4>Background</h4>The pathophysiology of xerosis depends on extrinsic and intrinsic exposures. Residential hard water may constitute such an exposure.<h4>Objectives</h4>To estimate the prevalence of xerosis and to compare water hardness exposure in blood donors with and without xerosis.<h4>Methods</h4>In this retrospective cohort study in 2018-2019, blood donors with self-reported moderately or severely dry skin were compared to blood donors without dry skin. Blood donors with ichthyosis, lichen planus and psoriasis were excluded. Water hardness data was collected from the Geology Survey of Denmark and Greenland.<h4>Results</h4>Overall, 4,748 of 30,721 (15.5%; 95% confidence interval 15.1-15.9%) blood donors had xerosis. After excluding blood donors with ichthyosis, lichen planus and psoriasis, 4,416 blood donors (2,559 females; median age 38.4 years [interquartile range 28.0-49.8]; 700 smokers) remained in this study. Water softer than 12-24 degrees Deutsche härte was associated with decreased probability of xerosis (odds ratio 0.83; 95% confidence interval 0.74-0.94) and water harder than 12-24 degrees Deutsche härte was associated with increased probability of xerosis (odds ratio 1.22; 95% confidence interval 1.03-1.45). The association between water hardness and xerosis remained significant after excluding blood donors with dermatitis.<h4>Conclusions</h4>Water hardness is associated with xerosis independent of other dermatoses. |
format |
article |
author |
Mattias A S Henning Kristina S Ibler Henrik Ullum Christian Erikstrup Mie T Bruun Kristoffer S Burgdorf Khoa M Dinh Andreas Rigas Lise W Thørner Ole B Pedersen Gregor B Jemec |
author_facet |
Mattias A S Henning Kristina S Ibler Henrik Ullum Christian Erikstrup Mie T Bruun Kristoffer S Burgdorf Khoa M Dinh Andreas Rigas Lise W Thørner Ole B Pedersen Gregor B Jemec |
author_sort |
Mattias A S Henning |
title |
The association between water hardness and xerosis-Results from the Danish Blood Donor Study. |
title_short |
The association between water hardness and xerosis-Results from the Danish Blood Donor Study. |
title_full |
The association between water hardness and xerosis-Results from the Danish Blood Donor Study. |
title_fullStr |
The association between water hardness and xerosis-Results from the Danish Blood Donor Study. |
title_full_unstemmed |
The association between water hardness and xerosis-Results from the Danish Blood Donor Study. |
title_sort |
association between water hardness and xerosis-results from the danish blood donor study. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2021 |
url |
https://doaj.org/article/d35114992e0549a48dcbb9ba4b8a6ba0 |
work_keys_str_mv |
AT mattiasashenning theassociationbetweenwaterhardnessandxerosisresultsfromthedanishblooddonorstudy AT kristinasibler theassociationbetweenwaterhardnessandxerosisresultsfromthedanishblooddonorstudy AT henrikullum theassociationbetweenwaterhardnessandxerosisresultsfromthedanishblooddonorstudy AT christianerikstrup theassociationbetweenwaterhardnessandxerosisresultsfromthedanishblooddonorstudy AT mietbruun theassociationbetweenwaterhardnessandxerosisresultsfromthedanishblooddonorstudy AT kristoffersburgdorf theassociationbetweenwaterhardnessandxerosisresultsfromthedanishblooddonorstudy AT khoamdinh theassociationbetweenwaterhardnessandxerosisresultsfromthedanishblooddonorstudy AT andreasrigas theassociationbetweenwaterhardnessandxerosisresultsfromthedanishblooddonorstudy AT lisewthørner theassociationbetweenwaterhardnessandxerosisresultsfromthedanishblooddonorstudy AT olebpedersen theassociationbetweenwaterhardnessandxerosisresultsfromthedanishblooddonorstudy AT gregorbjemec theassociationbetweenwaterhardnessandxerosisresultsfromthedanishblooddonorstudy AT mattiasashenning associationbetweenwaterhardnessandxerosisresultsfromthedanishblooddonorstudy AT kristinasibler associationbetweenwaterhardnessandxerosisresultsfromthedanishblooddonorstudy AT henrikullum associationbetweenwaterhardnessandxerosisresultsfromthedanishblooddonorstudy AT christianerikstrup associationbetweenwaterhardnessandxerosisresultsfromthedanishblooddonorstudy AT mietbruun associationbetweenwaterhardnessandxerosisresultsfromthedanishblooddonorstudy AT kristoffersburgdorf associationbetweenwaterhardnessandxerosisresultsfromthedanishblooddonorstudy AT khoamdinh associationbetweenwaterhardnessandxerosisresultsfromthedanishblooddonorstudy AT andreasrigas associationbetweenwaterhardnessandxerosisresultsfromthedanishblooddonorstudy AT lisewthørner associationbetweenwaterhardnessandxerosisresultsfromthedanishblooddonorstudy AT olebpedersen associationbetweenwaterhardnessandxerosisresultsfromthedanishblooddonorstudy AT gregorbjemec associationbetweenwaterhardnessandxerosisresultsfromthedanishblooddonorstudy |
_version_ |
1718374973822730240 |