Recent Advances in Functional Carbon Quantum Dots for Antitumour

Rong Cai,1 Long Xiao,1 Meixiu Liu,1 Fengyi Du,2 Zhirong Wang1 1Central Laboratory, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Suzhou, Jiangsu, 215600, People’s Republic of China; 2School of Medicine, Zhenjiang, Jiangsu, 212013, People’s Republic of ChinaCorrespon...

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Autores principales:	Cai R, Xiao L, Liu M, Du F, Wang Z
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	cqds antitumour drug delivery phototherapy Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/d35f3ed1246d4dad80ca1ac364b802f7
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spelling	oai:doaj.org-article:d35f3ed1246d4dad80ca1ac364b802f72021-12-02T19:35:47ZRecent Advances in Functional Carbon Quantum Dots for Antitumour1178-2013https://doaj.org/article/d35f3ed1246d4dad80ca1ac364b802f72021-10-01T00:00:00Zhttps://www.dovepress.com/recent-advances-in-functional-carbon-quantum-dots-for-antitumour-peer-reviewed-fulltext-article-IJNhttps://doaj.org/toc/1178-2013Rong Cai,1 Long Xiao,1 Meixiu Liu,1 Fengyi Du,2 Zhirong Wang1 1Central Laboratory, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Suzhou, Jiangsu, 215600, People’s Republic of China; 2School of Medicine, Zhenjiang, Jiangsu, 212013, People’s Republic of ChinaCorrespondence: Zhirong Wang; Fengyi Du Tel +86 138 6222 4593; +86 159 5290 0513Email zjgfy_spine_wzr@njucm.edu.cn; biodfy@ujs.edu.cnAbstract: Carbon quantum dots (CQDs) are an emerging class of quasi-zero-dimensional photoluminescent nanomaterials with particle sizes less than 10 nm. Owing to their favourable water dispersion, strong chemical inertia, stable optical performance, and good biocompatibility, CQDs have become prominent in biomedical fields. CQDs can be fabricated by “top-down” and “bottom-up” methods, both of which involve oxidation, carbonization, pyrolysis and polymerization. The functions of CQDs include biological imaging, biosensing, drug delivery, gene carrying, antimicrobial performance, photothermal ablation and so on, which enable them to be utilized in antitumour applications. The purpose of this review is to summarize the research progress of CQDs in antitumour applications from preparation and characterization to application prospects. Furthermore, the challenges and opportunities of CQDs are discussed along with future perspectives for precise individual therapy of tumours.Keywords: CQDs, antitumour, drug delivery, phototherapyCai RXiao LLiu MDu FWang ZDove Medical Pressarticlecqdsantitumourdrug deliveryphototherapyMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 16, Pp 7195-7229 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cqds antitumour drug delivery phototherapy Medicine (General) R5-920
spellingShingle	cqds antitumour drug delivery phototherapy Medicine (General) R5-920 Cai R Xiao L Liu M Du F Wang Z Recent Advances in Functional Carbon Quantum Dots for Antitumour
description	Rong Cai,1 Long Xiao,1 Meixiu Liu,1 Fengyi Du,2 Zhirong Wang1 1Central Laboratory, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Suzhou, Jiangsu, 215600, People’s Republic of China; 2School of Medicine, Zhenjiang, Jiangsu, 212013, People’s Republic of ChinaCorrespondence: Zhirong Wang; Fengyi Du Tel +86 138 6222 4593; +86 159 5290 0513Email zjgfy_spine_wzr@njucm.edu.cn; biodfy@ujs.edu.cnAbstract: Carbon quantum dots (CQDs) are an emerging class of quasi-zero-dimensional photoluminescent nanomaterials with particle sizes less than 10 nm. Owing to their favourable water dispersion, strong chemical inertia, stable optical performance, and good biocompatibility, CQDs have become prominent in biomedical fields. CQDs can be fabricated by “top-down” and “bottom-up” methods, both of which involve oxidation, carbonization, pyrolysis and polymerization. The functions of CQDs include biological imaging, biosensing, drug delivery, gene carrying, antimicrobial performance, photothermal ablation and so on, which enable them to be utilized in antitumour applications. The purpose of this review is to summarize the research progress of CQDs in antitumour applications from preparation and characterization to application prospects. Furthermore, the challenges and opportunities of CQDs are discussed along with future perspectives for precise individual therapy of tumours.Keywords: CQDs, antitumour, drug delivery, phototherapy
format	article
author	Cai R Xiao L Liu M Du F Wang Z
author_facet	Cai R Xiao L Liu M Du F Wang Z
author_sort	Cai R
title	Recent Advances in Functional Carbon Quantum Dots for Antitumour
title_short	Recent Advances in Functional Carbon Quantum Dots for Antitumour
title_full	Recent Advances in Functional Carbon Quantum Dots for Antitumour
title_fullStr	Recent Advances in Functional Carbon Quantum Dots for Antitumour
title_full_unstemmed	Recent Advances in Functional Carbon Quantum Dots for Antitumour
title_sort	recent advances in functional carbon quantum dots for antitumour
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/d35f3ed1246d4dad80ca1ac364b802f7
work_keys_str_mv	AT cair recentadvancesinfunctionalcarbonquantumdotsforantitumour AT xiaol recentadvancesinfunctionalcarbonquantumdotsforantitumour AT lium recentadvancesinfunctionalcarbonquantumdotsforantitumour AT duf recentadvancesinfunctionalcarbonquantumdotsforantitumour AT wangz recentadvancesinfunctionalcarbonquantumdotsforantitumour
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Recent Advances in Functional Carbon Quantum Dots for Antitumour

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