De novo compartment deconvolution and weight estimation of tumor samples using DECODER

Separating different cell compartments from bulk gene expression data can be challenging. Here the authors present DECODER, which can perform de novo deconvolutions on non-negative matrices including microarray, RNA-seq and ATAC-seq data sets.

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Autores principales: Xianlu Laura Peng, Richard A. Moffitt, Robert J. Torphy, Keith E. Volmar, Jen Jen Yeh
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/d36eff381c324e13b089aca37650d569
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spelling oai:doaj.org-article:d36eff381c324e13b089aca37650d5692021-12-02T15:36:02ZDe novo compartment deconvolution and weight estimation of tumor samples using DECODER10.1038/s41467-019-12517-72041-1723https://doaj.org/article/d36eff381c324e13b089aca37650d5692019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12517-7https://doaj.org/toc/2041-1723Separating different cell compartments from bulk gene expression data can be challenging. Here the authors present DECODER, which can perform de novo deconvolutions on non-negative matrices including microarray, RNA-seq and ATAC-seq data sets.Xianlu Laura PengRichard A. MoffittRobert J. TorphyKeith E. VolmarJen Jen YehNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xianlu Laura Peng
Richard A. Moffitt
Robert J. Torphy
Keith E. Volmar
Jen Jen Yeh
De novo compartment deconvolution and weight estimation of tumor samples using DECODER
description Separating different cell compartments from bulk gene expression data can be challenging. Here the authors present DECODER, which can perform de novo deconvolutions on non-negative matrices including microarray, RNA-seq and ATAC-seq data sets.
format article
author Xianlu Laura Peng
Richard A. Moffitt
Robert J. Torphy
Keith E. Volmar
Jen Jen Yeh
author_facet Xianlu Laura Peng
Richard A. Moffitt
Robert J. Torphy
Keith E. Volmar
Jen Jen Yeh
author_sort Xianlu Laura Peng
title De novo compartment deconvolution and weight estimation of tumor samples using DECODER
title_short De novo compartment deconvolution and weight estimation of tumor samples using DECODER
title_full De novo compartment deconvolution and weight estimation of tumor samples using DECODER
title_fullStr De novo compartment deconvolution and weight estimation of tumor samples using DECODER
title_full_unstemmed De novo compartment deconvolution and weight estimation of tumor samples using DECODER
title_sort de novo compartment deconvolution and weight estimation of tumor samples using decoder
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/d36eff381c324e13b089aca37650d569
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AT robertjtorphy denovocompartmentdeconvolutionandweightestimationoftumorsamplesusingdecoder
AT keithevolmar denovocompartmentdeconvolutionandweightestimationoftumorsamplesusingdecoder
AT jenjenyeh denovocompartmentdeconvolutionandweightestimationoftumorsamplesusingdecoder
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