De novo compartment deconvolution and weight estimation of tumor samples using DECODER
Separating different cell compartments from bulk gene expression data can be challenging. Here the authors present DECODER, which can perform de novo deconvolutions on non-negative matrices including microarray, RNA-seq and ATAC-seq data sets.
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Nature Portfolio
2019
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oai:doaj.org-article:d36eff381c324e13b089aca37650d5692021-12-02T15:36:02ZDe novo compartment deconvolution and weight estimation of tumor samples using DECODER10.1038/s41467-019-12517-72041-1723https://doaj.org/article/d36eff381c324e13b089aca37650d5692019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12517-7https://doaj.org/toc/2041-1723Separating different cell compartments from bulk gene expression data can be challenging. Here the authors present DECODER, which can perform de novo deconvolutions on non-negative matrices including microarray, RNA-seq and ATAC-seq data sets.Xianlu Laura PengRichard A. MoffittRobert J. TorphyKeith E. VolmarJen Jen YehNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019) |
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Science Q Xianlu Laura Peng Richard A. Moffitt Robert J. Torphy Keith E. Volmar Jen Jen Yeh De novo compartment deconvolution and weight estimation of tumor samples using DECODER |
description |
Separating different cell compartments from bulk gene expression data can be challenging. Here the authors present DECODER, which can perform de novo deconvolutions on non-negative matrices including microarray, RNA-seq and ATAC-seq data sets. |
format |
article |
author |
Xianlu Laura Peng Richard A. Moffitt Robert J. Torphy Keith E. Volmar Jen Jen Yeh |
author_facet |
Xianlu Laura Peng Richard A. Moffitt Robert J. Torphy Keith E. Volmar Jen Jen Yeh |
author_sort |
Xianlu Laura Peng |
title |
De novo compartment deconvolution and weight estimation of tumor samples using DECODER |
title_short |
De novo compartment deconvolution and weight estimation of tumor samples using DECODER |
title_full |
De novo compartment deconvolution and weight estimation of tumor samples using DECODER |
title_fullStr |
De novo compartment deconvolution and weight estimation of tumor samples using DECODER |
title_full_unstemmed |
De novo compartment deconvolution and weight estimation of tumor samples using DECODER |
title_sort |
de novo compartment deconvolution and weight estimation of tumor samples using decoder |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/d36eff381c324e13b089aca37650d569 |
work_keys_str_mv |
AT xianlulaurapeng denovocompartmentdeconvolutionandweightestimationoftumorsamplesusingdecoder AT richardamoffitt denovocompartmentdeconvolutionandweightestimationoftumorsamplesusingdecoder AT robertjtorphy denovocompartmentdeconvolutionandweightestimationoftumorsamplesusingdecoder AT keithevolmar denovocompartmentdeconvolutionandweightestimationoftumorsamplesusingdecoder AT jenjenyeh denovocompartmentdeconvolutionandweightestimationoftumorsamplesusingdecoder |
_version_ |
1718386384153083904 |