Multi-step screening of neoantigens’ HLA- and TCR-interfaces improves prediction of survival

Multi-step screening of neoantigens’ HLA- and TCR-interfaces improves prediction of survival

Abstract Improvement of risk stratification through prognostic biomarkers may enhance the personalization of cancer patient monitoring and treatment. We used Ancer, an immunoinformatic CD8, CD4, and regulatory T cell neoepitope screening system, to perform an advanced neoantigen analysis of genomic...

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Bibliographic Details
Main Authors: Guilhem Richard, Anne S. De Groot, Gary D. Steinberg, Tzintzuni I. Garcia, Alec Kacew, Matthew Ardito, William D. Martin, Gad Berdugo, Michael F. Princiotta, Arjun V. Balar, Randy F. Sweis
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/d371f9d2ea90470a84bf2e9f0ded5167
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https://doaj.org/article/d371f9d2ea90470a84bf2e9f0ded5167

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