Kleine-Levin syndrome: a review

Mitchell G Miglis, Christian Guilleminault Stanford University Sleep Medicine Division, Stanford Outpatient Medical Center, Redwood City, CA, USA Abstract: Kleine-Levin syndrome is a recurrent hypersomnia associated with symptoms of hyperphagia, hypersexuality, and cognitive impairment. This artic...

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Autores principales:	Guilleminault C, Miglis MG
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Psychiatry RC435-571 Neurophysiology and neuropsychology QP351-495
Acceso en línea:	https://doaj.org/article/d379b56f693543b2a81f31e793e2376b
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spelling	oai:doaj.org-article:d379b56f693543b2a81f31e793e2376b2021-12-02T07:51:03ZKleine-Levin syndrome: a review1179-1608https://doaj.org/article/d379b56f693543b2a81f31e793e2376b2014-01-01T00:00:00Zhttp://www.dovepress.com/kleine-levin-syndrome-a-review-a15572https://doaj.org/toc/1179-1608 Mitchell G Miglis, Christian Guilleminault Stanford University Sleep Medicine Division, Stanford Outpatient Medical Center, Redwood City, CA, USA Abstract: Kleine-Levin syndrome is a recurrent hypersomnia associated with symptoms of hyperphagia, hypersexuality, and cognitive impairment. This article reviews the current available research and describes common clinical symptoms, differential diagnosis, and acceptable workup and treatment. Although deficits have traditionally been thought to resolve between episodes, functional imaging studies and long-term neuropsychological testing in select patients have recently challenged this notion. This may suggest that Kleine-Levin syndrome is not as benign as previously considered. Keywords: Kleine-Levin syndrome, hypersomnia, adolescent sleep disorder, hypersexualityGuilleminault CMiglis MGDove Medical PressarticlePsychiatryRC435-571Neurophysiology and neuropsychologyQP351-495ENNature and Science of Sleep, Vol 2014, Iss default, Pp 19-26 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Psychiatry RC435-571 Neurophysiology and neuropsychology QP351-495
spellingShingle	Psychiatry RC435-571 Neurophysiology and neuropsychology QP351-495 Guilleminault C Miglis MG Kleine-Levin syndrome: a review
description	Mitchell G Miglis, Christian Guilleminault Stanford University Sleep Medicine Division, Stanford Outpatient Medical Center, Redwood City, CA, USA Abstract: Kleine-Levin syndrome is a recurrent hypersomnia associated with symptoms of hyperphagia, hypersexuality, and cognitive impairment. This article reviews the current available research and describes common clinical symptoms, differential diagnosis, and acceptable workup and treatment. Although deficits have traditionally been thought to resolve between episodes, functional imaging studies and long-term neuropsychological testing in select patients have recently challenged this notion. This may suggest that Kleine-Levin syndrome is not as benign as previously considered. Keywords: Kleine-Levin syndrome, hypersomnia, adolescent sleep disorder, hypersexuality
format	article
author	Guilleminault C Miglis MG
author_facet	Guilleminault C Miglis MG
author_sort	Guilleminault C
title	Kleine-Levin syndrome: a review
title_short	Kleine-Levin syndrome: a review
title_full	Kleine-Levin syndrome: a review
title_fullStr	Kleine-Levin syndrome: a review
title_full_unstemmed	Kleine-Levin syndrome: a review
title_sort	kleine-levin syndrome: a review
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/d379b56f693543b2a81f31e793e2376b
work_keys_str_mv	AT guilleminaultc kleinelevinsyndromeareview AT miglismg kleinelevinsyndromeareview
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Kleine-Levin syndrome: a review

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