Target-responsive vasoactive probes for ultrasensitive molecular imaging

Noninvasive detection of molecular targets in living subjects could provide valuable insights into healthy function and disease. Here, the authors develop vasoactive imaging probes which allow wide-field in vivo mapping of nanomolar-level molecular species in rat brain.

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Detalles Bibliográficos
Autores principales: Robert Ohlendorf, Agata Wiśniowska, Mitul Desai, Ali Barandov, Adrian L. Slusarczyk, Nan Li, Alan Jasanoff
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/d3830fd1f7e24335a4dd426dd07066e3
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Descripción
Sumario:Noninvasive detection of molecular targets in living subjects could provide valuable insights into healthy function and disease. Here, the authors develop vasoactive imaging probes which allow wide-field in vivo mapping of nanomolar-level molecular species in rat brain.