Chronic Intractable Pruritus in Chronic Kidney Disease Patients: Prevalence, Impact, and Management Challenges — A Narrative Review

Chronic Intractable Pruritus in Chronic Kidney Disease Patients: Prevalence, Impact, and Management Challenges — A Narrative Review

Karolina Świerczyńska, Rafał Białynicki-Birula, Jacek C Szepietowski Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Wroclaw, PolandCorrespondence: Jacek C SzepietowskiDepartment of Dermatology, Venereology and Allergolo...

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Autores principales: Świerczyńska K, Białynicki-Birula R, Szepietowski JC
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2021
Materias:
chronic kidney disease
chronic kidney disease-associated pruritus
treatment
Therapeutics. Pharmacology
RM1-950
Acceso en línea:https://doaj.org/article/d388e2adcf36474a8f645d4b9c0ec093
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spelling oai:doaj.org-article:d388e2adcf36474a8f645d4b9c0ec0932021-11-30T18:50:37ZChronic Intractable Pruritus in Chronic Kidney Disease Patients: Prevalence, Impact, and Management Challenges — A Narrative Review1178-203Xhttps://doaj.org/article/d388e2adcf36474a8f645d4b9c0ec0932021-11-01T00:00:00Zhttps://www.dovepress.com/chronic-intractable-pruritus-in-chronic-kidney-disease-patients-preval-peer-reviewed-fulltext-article-TCRMhttps://doaj.org/toc/1178-203XKarolina Świerczyńska, Rafał Białynicki-Birula, Jacek C Szepietowski Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Wroclaw, PolandCorrespondence: Jacek C SzepietowskiDepartment of Dermatology, Venereology and Allergology, Wroclaw Medical University, 1 Chalubinskiego Street, Wroclaw, 50-368, PolandTel +48 601 534 853Fax +48 71 327 09 42Email jacek.szepietowski@umed.wroc.plAbstract: Chronic kidney disease (CKD) is recognized as a leading public health problem and causes numerous health complications. One of the most common and burdensome dermatological symptoms affecting patients undergoing dialysis is CKD-associated pruritus (CKD-aP). This condition not only has a negative impact on sleep, mood, daily activities, and quality of life but also increases the mortality risk of hemodialyzed patients. Despite that, this condition is greatly underestimated in clinical practice. Due to the complex and still not fully understood etiopathogenesis of CKD-aP, the choice of an effective therapy remains a challenge for clinicians. Most common therapeutic algorithms use topical treatment, phototherapy, and various systemic approaches. This review aimed to summarize most recent theories about the pathogenesis, clinical features, and treatment of CKD-aP.Keywords: chronic kidney disease, chronic kidney disease–associated pruritus, treatmentŚwierczyńska KBiałynicki-Birula RSzepietowski JCDove Medical Pressarticlechronic kidney diseasechronic kidney disease-associated pruritustreatmentTherapeutics. PharmacologyRM1-950ENTherapeutics and Clinical Risk Management, Vol Volume 17, Pp 1267-1282 (2021)
institution DOAJ
collection DOAJ
language EN
topic chronic kidney disease
chronic kidney disease-associated pruritus
treatment
Therapeutics. Pharmacology
RM1-950
spellingShingle chronic kidney disease
chronic kidney disease-associated pruritus
treatment
Therapeutics. Pharmacology
RM1-950
Świerczyńska K
Białynicki-Birula R
Szepietowski JC
Chronic Intractable Pruritus in Chronic Kidney Disease Patients: Prevalence, Impact, and Management Challenges — A Narrative Review
description Karolina Świerczyńska, Rafał Białynicki-Birula, Jacek C Szepietowski Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Wroclaw, PolandCorrespondence: Jacek C SzepietowskiDepartment of Dermatology, Venereology and Allergology, Wroclaw Medical University, 1 Chalubinskiego Street, Wroclaw, 50-368, PolandTel +48 601 534 853Fax +48 71 327 09 42Email jacek.szepietowski@umed.wroc.plAbstract: Chronic kidney disease (CKD) is recognized as a leading public health problem and causes numerous health complications. One of the most common and burdensome dermatological symptoms affecting patients undergoing dialysis is CKD-associated pruritus (CKD-aP). This condition not only has a negative impact on sleep, mood, daily activities, and quality of life but also increases the mortality risk of hemodialyzed patients. Despite that, this condition is greatly underestimated in clinical practice. Due to the complex and still not fully understood etiopathogenesis of CKD-aP, the choice of an effective therapy remains a challenge for clinicians. Most common therapeutic algorithms use topical treatment, phototherapy, and various systemic approaches. This review aimed to summarize most recent theories about the pathogenesis, clinical features, and treatment of CKD-aP.Keywords: chronic kidney disease, chronic kidney disease–associated pruritus, treatment
format article
author Świerczyńska K
Białynicki-Birula R
Szepietowski JC
author_facet Świerczyńska K
Białynicki-Birula R
Szepietowski JC
author_sort Świerczyńska K
title Chronic Intractable Pruritus in Chronic Kidney Disease Patients: Prevalence, Impact, and Management Challenges — A Narrative Review
title_short Chronic Intractable Pruritus in Chronic Kidney Disease Patients: Prevalence, Impact, and Management Challenges — A Narrative Review
title_full Chronic Intractable Pruritus in Chronic Kidney Disease Patients: Prevalence, Impact, and Management Challenges — A Narrative Review
title_fullStr Chronic Intractable Pruritus in Chronic Kidney Disease Patients: Prevalence, Impact, and Management Challenges — A Narrative Review
title_full_unstemmed Chronic Intractable Pruritus in Chronic Kidney Disease Patients: Prevalence, Impact, and Management Challenges — A Narrative Review
title_sort chronic intractable pruritus in chronic kidney disease patients: prevalence, impact, and management challenges — a narrative review
publisher Dove Medical Press
publishDate 2021
url https://doaj.org/article/d388e2adcf36474a8f645d4b9c0ec093
work_keys_str_mv AT swierczynskak chronicintractablepruritusinchronickidneydiseasepatientsprevalenceimpactandmanagementchallengesmdashanarrativereview
AT białynickibirular chronicintractablepruritusinchronickidneydiseasepatientsprevalenceimpactandmanagementchallengesmdashanarrativereview
AT szepietowskijc chronicintractablepruritusinchronickidneydiseasepatientsprevalenceimpactandmanagementchallengesmdashanarrativereview
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