Experimental Bioactive Glass-Containing Composites and Commercial Restorative Materials: Anti-Demineralizing Protection of Dentin

The purpose of this in vitro study was to investigate whether different types of experimental and commercial restorative dental materials can protect dentin against acid-induced softening. Experimental composites were prepared with a photocurable mixture of methacrylates and two types of bioactive g...

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Autores principales: Matej Par, Andrea Gubler, Thomas Attin, Zrinka Tarle, Andro Tarle, Tobias T. Tauböck
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Lenguaje:EN
Publicado: MDPI AG 2021
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spelling oai:doaj.org-article:d394db83c2374dfcb8ca593b6ddafa762021-11-25T16:49:39ZExperimental Bioactive Glass-Containing Composites and Commercial Restorative Materials: Anti-Demineralizing Protection of Dentin10.3390/biomedicines91116162227-9059https://doaj.org/article/d394db83c2374dfcb8ca593b6ddafa762021-11-01T00:00:00Zhttps://www.mdpi.com/2227-9059/9/11/1616https://doaj.org/toc/2227-9059The purpose of this in vitro study was to investigate whether different types of experimental and commercial restorative dental materials can protect dentin against acid-induced softening. Experimental composites were prepared with a photocurable mixture of methacrylates and two types of bioactive glass (45S5 and a customized low-Na F-containing formulation). Human dentin samples were prepared from mid-coronal tooth slices and immersed in lactic acid solution (pH = 4.0) at 5 mm from set specimens of restorative material. After 4, 8, 12, 16, 20, 24, 28, and 32 days, surface microhardness of dentin samples and pH of the immersion solution were measured, followed by replenishing of the immersion medium. Microstructural analysis was performed using scanning electron microscopy. The protective effect of restorative materials was determined as dentin microhardness remaining statistically similar to initial values for a certain number of acid additions. Scanning electron microscopy showed a gradual widening of dentinal tubules and proved less discriminatory than microhardness measurements. To produce a protective effect on dentin, 20 wt% of low-Na F-containing bioactive glass was needed, whereas 10 wt% of bioactive glass 45S5 was sufficient to protect dentin against acid-induced demineralization. The anti-demineralizing protective effect of experimental and commercial restoratives on dentin was of shorter duration than measured for enamel in a previous study using the same experimental approach.Matej ParAndrea GublerThomas AttinZrinka TarleAndro TarleTobias T. TauböckMDPI AGarticleexperimental resin compositesremineralizing dental materialsbioactive glassglass ionomeralkasitegiomerBiology (General)QH301-705.5ENBiomedicines, Vol 9, Iss 1616, p 1616 (2021)
institution DOAJ
collection DOAJ
language EN
topic experimental resin composites
remineralizing dental materials
bioactive glass
glass ionomer
alkasite
giomer
Biology (General)
QH301-705.5
spellingShingle experimental resin composites
remineralizing dental materials
bioactive glass
glass ionomer
alkasite
giomer
Biology (General)
QH301-705.5
Matej Par
Andrea Gubler
Thomas Attin
Zrinka Tarle
Andro Tarle
Tobias T. Tauböck
Experimental Bioactive Glass-Containing Composites and Commercial Restorative Materials: Anti-Demineralizing Protection of Dentin
description The purpose of this in vitro study was to investigate whether different types of experimental and commercial restorative dental materials can protect dentin against acid-induced softening. Experimental composites were prepared with a photocurable mixture of methacrylates and two types of bioactive glass (45S5 and a customized low-Na F-containing formulation). Human dentin samples were prepared from mid-coronal tooth slices and immersed in lactic acid solution (pH = 4.0) at 5 mm from set specimens of restorative material. After 4, 8, 12, 16, 20, 24, 28, and 32 days, surface microhardness of dentin samples and pH of the immersion solution were measured, followed by replenishing of the immersion medium. Microstructural analysis was performed using scanning electron microscopy. The protective effect of restorative materials was determined as dentin microhardness remaining statistically similar to initial values for a certain number of acid additions. Scanning electron microscopy showed a gradual widening of dentinal tubules and proved less discriminatory than microhardness measurements. To produce a protective effect on dentin, 20 wt% of low-Na F-containing bioactive glass was needed, whereas 10 wt% of bioactive glass 45S5 was sufficient to protect dentin against acid-induced demineralization. The anti-demineralizing protective effect of experimental and commercial restoratives on dentin was of shorter duration than measured for enamel in a previous study using the same experimental approach.
format article
author Matej Par
Andrea Gubler
Thomas Attin
Zrinka Tarle
Andro Tarle
Tobias T. Tauböck
author_facet Matej Par
Andrea Gubler
Thomas Attin
Zrinka Tarle
Andro Tarle
Tobias T. Tauböck
author_sort Matej Par
title Experimental Bioactive Glass-Containing Composites and Commercial Restorative Materials: Anti-Demineralizing Protection of Dentin
title_short Experimental Bioactive Glass-Containing Composites and Commercial Restorative Materials: Anti-Demineralizing Protection of Dentin
title_full Experimental Bioactive Glass-Containing Composites and Commercial Restorative Materials: Anti-Demineralizing Protection of Dentin
title_fullStr Experimental Bioactive Glass-Containing Composites and Commercial Restorative Materials: Anti-Demineralizing Protection of Dentin
title_full_unstemmed Experimental Bioactive Glass-Containing Composites and Commercial Restorative Materials: Anti-Demineralizing Protection of Dentin
title_sort experimental bioactive glass-containing composites and commercial restorative materials: anti-demineralizing protection of dentin
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/d394db83c2374dfcb8ca593b6ddafa76
work_keys_str_mv AT matejpar experimentalbioactiveglasscontainingcompositesandcommercialrestorativematerialsantidemineralizingprotectionofdentin
AT andreagubler experimentalbioactiveglasscontainingcompositesandcommercialrestorativematerialsantidemineralizingprotectionofdentin
AT thomasattin experimentalbioactiveglasscontainingcompositesandcommercialrestorativematerialsantidemineralizingprotectionofdentin
AT zrinkatarle experimentalbioactiveglasscontainingcompositesandcommercialrestorativematerialsantidemineralizingprotectionofdentin
AT androtarle experimentalbioactiveglasscontainingcompositesandcommercialrestorativematerialsantidemineralizingprotectionofdentin
AT tobiasttaubock experimentalbioactiveglasscontainingcompositesandcommercialrestorativematerialsantidemineralizingprotectionofdentin
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