Arginase 2 and Polyamines in Human Pancreatic Beta Cells: Possible Role in the Pathogenesis of Type 2 Diabetes
Arginase 2 (ARG2) is a manganese metalloenzyme involved in several tissue specific processes, from physiology to pathophysiology. It is variably expressed in extra-hepatic tissues and is located in the mitochondria. In human pancreatic beta cells, ARG2 is downregulated in type 2 diabetes. The enzyme...
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Main Authors: | Lorella Marselli, Emanuele Bosi, Carmela De Luca, Silvia Del Guerra, Marta Tesi, Mara Suleiman, Piero Marchetti |
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Format: | article |
Language: | EN |
Published: |
MDPI AG
2021
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Online Access: | https://doaj.org/article/d39db0ce76f1418cb7eeec62287d27f2 |
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