Arginase 2 and Polyamines in Human Pancreatic Beta Cells: Possible Role in the Pathogenesis of Type 2 Diabetes

Arginase 2 (ARG2) is a manganese metalloenzyme involved in several tissue specific processes, from physiology to pathophysiology. It is variably expressed in extra-hepatic tissues and is located in the mitochondria. In human pancreatic beta cells, ARG2 is downregulated in type 2 diabetes. The enzyme...

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Bibliographic Details
Main Authors: Lorella Marselli, Emanuele Bosi, Carmela De Luca, Silvia Del Guerra, Marta Tesi, Mara Suleiman, Piero Marchetti
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/d39db0ce76f1418cb7eeec62287d27f2
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