Upregulation of SK3 and IK1 channels contributes to the enhanced endothelial calcium signaling and the preserved coronary relaxation in obese Zucker rats.

<h4>Background and aims</h4>Endothelial small- and intermediate-conductance KCa channels, SK3 and IK1, are key mediators in the endothelium-derived hyperpolarization and relaxation of vascular smooth muscle and also in the modulation of endothelial Ca2+ signaling and nitric oxide (NO) re...

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Autores principales: Belén Climent, Laura Moreno, Pilar Martínez, Cristina Contreras, Ana Sánchez, Francisco Pérez-Vizcaíno, Albino García-Sacristán, Luis Rivera, Dolores Prieto
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/d39e580b192145d9bede6cb891057c6a
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