Co-option of the cardiac transcription factor Nkx2.5 during development of the emu wing

The transcription factor Nkx2.5 is essential for heart development. Here, the authors identify a previously unknown expression domain for Nkx2.5 in the emu wing and explore its role in diminished wing bud development in the flightless emu, compared with three other birds that have functional wings.

Guardado en:
Detalles Bibliográficos
Autores principales: Peter G. Farlie, Nadia M. Davidson, Naomi L. Baker, Mai Raabus, Kelly N. Roeszler, Claire Hirst, Andrew Major, Mylene M. Mariette, David M. Lambert, Alicia Oshlack, Craig A. Smith
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/d39fc2c1c3a943f48666365a2d6c0c28
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:The transcription factor Nkx2.5 is essential for heart development. Here, the authors identify a previously unknown expression domain for Nkx2.5 in the emu wing and explore its role in diminished wing bud development in the flightless emu, compared with three other birds that have functional wings.